This study was conducted to investigate the effect of plant parts on impaired liver function by injecting rats with carbon tetrachloride (CCl 4 ). Thirty five adult male albino rats weighing 150 ±10g were divided into two main groups and five sub groups, each with five rats. One of main groups (not injected) was considered as negative control group which fed on standard diet and tap water, and the other main group was fed on standard diet and injected s/c by carbon tetrachloride (CCl 4 ) in olive oil 50% v/v (3ml/kg. B.wt.) twice a week for two weeks to induce hepatointoxication. This main group was divided into 6 groups to be fed on the experimental diets for (4) weeks according to the following : Group (2) :Positive control group (untreated group) , Group(3):Feeding with 5g/100g Flowers, Group (4): Feeding with 5g/100g Leaves, Group (5) :Feeding with 5g/100g Stems, Group (6) : Feeding with 5g/100g Roots, Group (7): Feeding with 5g/100g Seeds of berseem plant. At the end of experiment (4 weeks), the blood samples were collected after 12 hours fasting and serum was separated for determination of : Lipid profile:Total cholesterol (T.C),triglycerides (T.G), high density lipoprotein (HDL-C),low density lipo protein (LDL-C), very low density lipo protein (VLDL-C) and Atherogenic Index (AI) ,Serum glucose,Serum liver functions: Aspartate amino transaminase (AST), alanine amino transferase (ALT), alkaline phosphatase (ALP), (AST/ALT) ratio,total protein, albumin, globulin, albumin/globulin ratio,total bilirubin, direct bilirubin, and indirect bilirubin, serum antioxidant enzymes: Glutathione peroxidase (GPX), Superoxide dismutase (SOD) and Catalase (CAT) and kidney functions (urea , creatinine ,uric acid).At the same time, the organs :Liver, Heart, Spleen ,

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The ongoing study highlights the effect of some plants which include (Costus speciosus-Solenostemma Argel-Phyllanthus emblica and their mixture) to treat hypercholeaterolemia. Rat's hypercholesterolemia was induced in normal healthy male albino rats by Cholesterol feeding for 2 weeks on diet containing 1.5% cholesterol plus 10% sheep tail fat. It total number of (42) mature male albino rats of Sprague -dawley strain weighting 180-200 g rats were divided into 6 groups (7rats in each group ). One of them used as control positive(+ve)group, second as control negative(-ve) and others groups from 3-6 fed on diets and containing plants extracts at dose (400 mg/kg b.w.) for 28 days orally. At the end of experimental period blood samples were collected for serum separation to evaluate liver function (AST,ALT&ALP), kidney function (uric acid , urea & creatinine) , internal organs Weights % of b.w. , lipids profile(TG -TC-LDL-VLDL-HDL),& histopathological change of liver. Results of present investigation revealed that all tested plants improved previous phytochemical parameters, but mixtured extract(Mix) was the best treatment in practicular Histopathological changes for liver, showed remarkable recovery of liver tissues, for all groups especially the mix group which indicated maximum recovery possibly due to phytochemicals compared to livers of control (+)ve group which was showing hyperplasia of epithelial lining bile duct& fibro-plasia in portal triad ,besides sinusoidal leucocytosis. The results of present work suggestes the use of tested plantes for clinical nutrition .

Oxidative stress plays an important role in the etiology and pathogenesis of many chronic diseases. Dietary intake of antioxidants can inhibit or delay the oxidation of susceptible cellular substrates so prevent oxidative stress. The present study was designed to investigate potential protective and ameliorate effects of pineapple and kumquat powders against potassium bromate (KBrO3)-induced oxidative stress using experimental rats. Whole kumquat (seedless), kumquat seeds, pineapple flesh and pineapple leaves were analyzed for phenolic compounds. Measurement of potential of cytotoxicity against the liver carcinoma cell line (HEPG2) carried out by SRB assay of the ethanolic extract of whole kumquat seedless, kumquat seeds, whole kumquat, pineapple flesh, pineapple leaves, pineapple (flesh +leaves) and mixture of them.

This investigation aimed to study the hypocholesteroiemic action of doum palm and leek seeds by the ratio 3 and 5% and probable effect on the weight gain, internal organs weight, feed intake and feed efficiency ratio as calculated for albino rats, and also to clear out their possible therapeutic impacts on the levels of serum glucose, lipid profile, liver functions and kidneys functions via feeding trials. The obtained results showed that the best treatment showing maximum decreasing of serum glucose observed for leek seeds as 5% and for alkaline phosphatase was observed for doum palm seeds as5%. The seeds of doum palm was benefical for correcting the serumlipid profile. The best treatments of serum glutamic oxaloacetate transaminase was that of doum palm seeds and also for serum glutamic pyruvate transaminase. Leek seeds was the best for kidneys functions.