Objective: to analyze the effects of LEGO® therapy as an intervention for autism spectrum disorder through an integrative literature review. Methods: the study included a search of electronic databases, and nine empirical studies and three books, detailing the intervention method, were selected. Results: the studies identified quantifiable improvements in social behavior and language/communication after LEGO® therapy. Conclusion: LEGO® therapy is an intervention that favors motivation, interaction, and teamwork using a material that allows a variety of strategies, which have shown proven positive effects on the development of children with ASD.