AKTIVITAS ANTIFUNGI EKSTRAK ETANOL BATANG BINAHONG (Anredera cordifolia(Tenore) Steen.) TERHADAPCandida albicansSERTA SKRINING FITOKIMIA

Kumalasari, Eka; Sulistyani, Nanik

doi:10.12928/pharmaciana.v1i2.524

Cited by 20 publications

(19 citation statements)

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“…Following agitation, a hydrophilic group binds with water, whereas a hydrophobic group binds with air and creates froth. The addition of 2N HCl was to increase polarity that the hydrophilic groups would bind more firmly and the froth would be more stable (Kumalasari, 2011). The aqueous extract also positively contains tannins due to the emergence of a blackish blue color after the addition of FeCl 3 .…”

Section: Resultsmentioning

confidence: 99%

Formulation and test activities of hair tonic with a combination of the aqueous extracts of aloe vera ( Aloe vera L.) and licorice (Glycyrrhiza glabra L.)

Indriaty

Indrawati

Taurhesia³

2018

Pharmaciana

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Aloe vera contains lignin, folic acid, vitamin A, and 20 types of amino acids, while Glycyrrhiza glabra L. contains glycyrrhizin, steroids, and beta-glycyrrhetinic acid that benefit for hair health. This research aimed to produce hair tonic with the best activity from the combination of aloe vera and licorice extract. The phytochemicals in the aqueous extract of licorice and Aloe vera were screened. The hair tonic was then prepared with 3 formulas using 7.5% Aloe vera extract and 2.5% licorice extract, as well as 96% ethanol with varying percentages, namely 5, 10, and 15%. Afterward, the formulas were tested for their activity as hair fertilizer on 4 white male rabbits for 28 days. The evaluation of hair tonic preparation included organoleptic observation, pH, specific weight, viscosity, and hedonic tests. It measured hair growth rate, the acceleration of hair growth, and hair weight. The results showed that hair tonic containing a mixture of 7.5% of Aloe vera extract, 2.5% of licorice extract, and 96% ethanol with different percentages (i.e., 5, 10, and 15%) created a good hair fertilizer. Hair tonic prepared with 15% of 96% ethanol exhibited an optimum activity. It was characterized by brown color, distinctive odor, homogeneity, a specific weight of 1.0577 g/mL, a viscosity of 2.8479 cP to distilled water, and pH 5.5. Its effectiveness as hair fertilizer was evidenced by a hair growth rate of 2.6617 cm in 28 days, a hair growth acceleration of 0.1635 cm/day, and a hair weight of 0.1854 gram in 28 days.

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Section: Resultsmentioning

confidence: 99%

Formulation and test activities of hair tonic with a combination of the aqueous extracts of aloe vera ( Aloe vera L.) and licorice (Glycyrrhiza glabra L.)

Indriaty

Indrawati

Taurhesia³

2018

Pharmaciana

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“…simplicia get results of 7.98%. Water content value of simplicia that exceeds 10% can be a good medium for microbial growth, presence of fungi or insects, and encourage damage due to hydrolysis process [15].…”

Section: Discussionmentioning

confidence: 99%

Anticancer Activity of Vernonia amygdalina Del. Extract on WiDr Colon Cancer Cell Line

Bestari¹,

Ichwan²,

Mustofa³

et al. 2018

Proceedings of the 2nd Public Health International Conference (PHICo 2017)

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Colon cancer is the third most common cancer in men and second in women. Cancer treatments include chemotherapy, but some chemotheraphy drugs are resistant. Vernonia amygdalina Del. is one of the most widely reported plant that can inhibit the growth of various cancer cell lines. This study aims to examine the anticancer activity of Vernonia amygdalina Del. extract on WiDr colon cancer cell line. This research is an experimental research in vitro using posttest only control group design. Research subjects are WiDr cells. The research method starts from preparation and characterization of simplicia, gradual maceration of Vernonia amygdalina Del. using n-hexane, ethyl acetate, and ethanol, phytochemical analysis of each extracts, cytotoxicity assay on WiDr cells using MTT (Microculture Tetrazolium Technique) assay. Ethyl acetate extract of Vernonia amygdalina Del. has the lowest IC 50 value in cytotoxicity assay results, indicate that ethyl acetate extract has very strong citotoxic activity on WiDr cells. Further studies are to analysis the mechanisms of ethyl acetate extracts in induce apoptosis, inhibition of cell cycle, and to observe the protein expression associated with it.

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“…1 penyakit infeksi jamur pada kulit sering dijumpai dikarenakan pola hidup yang kurang bersih, dan didukung dengan iklim tropis dengan kelembaban udara yang tinggi, sanitasi kurang, atau lingkungan padat penduduk sangat mendukung pertumbuhan jamur. 2 Sebagian besar infeksi jamur pada kulit disebabkan oleh jamur dari golongan Trichophyton dan Microsporum dengan bentuk infeksinya berupa tinea pedis, tinea unguium, tinea cruris, tinea capitis dan tinea corporis atau dermatofita. 3 Data rumah sakit Haji Adam Malik Medan pada tahun 2009-2012 menunjukkan prevalensi kasus dermatofita, tinea cruris 1026 kasus (39,9%), tinea corporis 572 kasus (22,2%), tinea pedis 203 kasus (7,9%), tinea capitis dan tinea barbae 111 kasus (4,3%), tinea unguium 102 kasus (4,0%), tinea manuum 47 kasus (1,8%), tinea imbrikata 6 kasus (0,2%), tinea nigra 1 kasus (0,03%) dan sisanya merupakan kasus non dermatofita.…”

Section: Pendahuluanunclassified

Aktivitas anti jamur ekstrak etanol daun kesum (<em>Polygonum minus Huds.</em>) terhadap jamur <em>Trichophyton mentagrophytes</em>

et al. 2019

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Dermatofitosis merupakan penyakit kulit yang diakibatkan oleh kolonisasi jamur dermatofita yang menyerang jaringan keratin epidermis bagian superfisial seperti kulit, kuku, dan rambut. Salah satu spesies terbanyak penyebab dermatofitosis yaitu Trichophyton mentagrophytes. Tanaman Kesum (Polygonum minus Huds.) memiliki kandungan senyawa metabolit sekunder yang berpotensi sebagai anti jamur. Tujuan: Penelitian ini bertujuan untuk mengetahui aktivitas anti jamur ekstrak etanol daun Kesum terhadap jamur Trichophyton mentagrophytes, dan mengetahui diameter zona hambat oleh ekstrak etanol daun Kesum terhadap Trichopyton mentagrophytes. Metode: Aktivitas anti jamur diuji dengan metode difusi cakram. Analisis metabolit sekunder ekstrak etanol daun Kesum menggunakan metode kromatografi lapis tipis. Kontrol positif yang digunakan adalah Itrakonazol 8µg, dan kontrol negatif adalah DMSO 10%. Hasil: Ekstrak etanol daun Kesum memiliki aktivitas anti jamur pada konsentrasi 40% dan 80% dengan rata-rata diameter zona hambat 10,125 mm dengan kategori sedang dan 20,625 mm dengan kategori sangat kuat. Hasil skrining fitokimia didapatkan terpenoid, flavonoid, alkaloid, saponin dan fenol. Simpulan: Ekstrak etanol daun Kesum berpotensi sebagai obat anti dermatofita terhadap Trichophyton mentagrophytes.

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AKTIVITAS ANTIFUNGI EKSTRAK ETANOL BATANG BINAHONG (Anredera cordifolia(Tenore) Steen.) TERHADAPCandida albicansSERTA SKRINING FITOKIMIA

Abstract: AbstrakBinahong (Anredera cordifolia (Tenore) (85; 86; 87; 88; 89; 90% b / v

Cited by 20 publications

References 0 publications

Formulation and test activities of hair tonic with a combination of the aqueous extracts of aloe vera ( Aloe vera L.) and licorice (Glycyrrhiza glabra L.)

Formulation and test activities of hair tonic with a combination of the aqueous extracts of aloe vera ( Aloe vera L.) and licorice (Glycyrrhiza glabra L.)

Anticancer Activity of Vernonia amygdalina Del. Extract on WiDr Colon Cancer Cell Line

Aktivitas anti jamur ekstrak etanol daun kesum (<em>Polygonum minus Huds.</em>) terhadap jamur <em>Trichophyton mentagrophytes</em>

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