Aktivitas Antijamur Minyak Atsiri Sereh Wangi (Cymbopogon Nardus (L.) Rendle)

Abstract

Citronella fragrance is one of the many plants in Indonesia. Citronella fragrance is widely used by Indonesian people as a spice dish and has traditionally been used for various treatments. Citronella fragrance contains essential oils that have the potential to have anti-fungal effects and have traditionally been used for the treatment of skin diseases. Isolation of citronella essential oil with the method of vapor distillation. The tested fungi are opportunistic fungi that often infect human skin. In testing the antifungal activity of the citronella essential oil (Cymbopogonnardus (L.) Rendle) against the fungal causing skin infection. The research was done by using agar diffusion method and using the density disc as the diffusion medium against A research of antifungal�s activity of essential oil of citronella (Cymbopogon nardus (L.) Rendle ) to fungus that cause disease in humans has been done. This research used agar diffusion method to the fungus test Tricophyton rubrum, Tricophyton mentagrophytes and Candida albicans. The concentration that used 1%, 0,5%, 0,25% and 0,1%. The results showed that in concentration 1% essential oil of citronella (Cymbopogon nardus ( L.)Rendle) has the highest activity with Candida albicans with an average of inhibition diameter was 19,4mm � 0,15. In 0,1% concentration of essential oil of citronella (Cymbopogon nardus (L.) Rendle) does not have antifungal�s activity to Tricophyton mentagrophytes that without inhibition diameter around the paper discs. Meanwhile, in concentration 0,1%, the essential oil of citronella (Cymbopogon nardus (L.) Rendle) still have antifungal�s activity to Tricophyton rubrum and Candida albicans with an average of inhibition diameter 7,4 mm � 0,35 dan 8,5 mm � 0,15. Keywords: Candida albicans, Sereh wangi (Cymbopogonnardus (L.), Tricophyton rubrum, Tricophyton mentagrophytes, Candida albicans

Isolation of Citronellal from Cymbopogon nardus (L) Rendle and its Activity Test as a Burn Healing in Mice

“…In the process of healing burns that occur can be hampered by its activity due to the bacteria Staphylococcus aureus and Pseoudomonas aeruginosa (Inawati, 2015). The mechanism of healing of burns, because citronellal compounds have antibacterial properties that inhibit the growth of S. aureus, S. epidermidis, P. aeruginosa, Streptococcus mutans (Jamaluddin et al, 2017) and have antifungal activities such as Ricophytonicrum and Tricophytonicrum (Jamaluddin et al 2017;Lely et al 2018). The presence of the citronellal compound as an antibacterial can help inhibit the growth of pathogenic bacteria and prevent infection in the wound, thereby speeding up the process of wound healing.…”

“…The distilled essential oil of lemongrass contained citronellal, citronellol and geraniol as three main compounds (Anwar, 2019). Citronellal has high antioxidant activity (Lawrence et al 2012), antibacterial activity that inhibits the growth of Staphylococcus aureus, S. epidermidis, Pseoudomonas aeruginosa, Streptococcus mutans (Jamaluddin et al, 2017), and antifungal activity against Tricophytonton tonrum, T. rubrum, T. mushroom, Stricus and Candida albicans (Lely et al, 2018). Based on previous studies, citronellal has potential as a therapy for burns because its ability to inhibit bacteria and fungi probably present in wound.…”

Pemberdayaan Masyarakat Desa Takuti Kecamatan Mataraman dalam Pemanfaatan Produk Berbasis Minyak Atsiri

“…Sereh atau Cymbopogon nardus L. termasuk dalam keluarga Poaceae yang mengadung minyak atsiri yang bersifat antibakteri alami. Senyawa aktif dari sereh yang dapat bersifat sebagai antibakteri dan antijamur adalah sitronelal dan linalool (Lely et al, 2018). Selain itu, sereh juga mengandung senyawa aktif seperti sitral, geraniol, dan metilheptan (Zaituni et al, 2016).…”

“…Selain itu, sereh juga mengandung senyawa aktif seperti sitral, geraniol, dan metilheptan (Zaituni et al, 2016). Minyak atsiri sereh dapat digunakan sebagai obat gosok, meredakan sakit kepala, mengatasi gigitan serangga, antibakteri, dan wewangian (Lely et al, 2018). Minyak atsiri sereh juga sudah banyak digunakan sebagai kosmetika, salah satunya adalah campuran dari sabun.…”

SKRINING FITOKIMIA, TOTAL FLAVONOID DAN FENOLIK DAUN SEREH WANGI (Cymbopogon nardus (L.) Rendle)

“…Tanaman sereh wangi digunakan sebagai bahan baku pembuatan minyak atsiri. Minyak atsiri dapat digunakan sebagai antijamur terhadap Trichopyton rubrum, Trichopyton mentangrophyton dan antibakteri Candida albicans (Lely, 2018). Dalam dunia perdagangan sebagai bahan dasar kosmetik, pembuatan parfum, obat-obatan, antiseptik, perisa makanan atau minuman serta pencampuran rokok kretek dan beberapa digunakan sebagai aerosol dan pembersih lantai, detergen, pewangi sabun sebagai antidepresi (Sulaswatty et al, 2019).…”