Antibacterial Activities of Sirih Merah (&lt;i&gt;Piper crocatum&lt;/i&gt;) Leaf Extracts

Puspita, Puspa Julistia; Safithri, Mega; Sugiharti, Nirmala Peni

doi:10.29244/cb.5.3.1-10

Cited by 25 publications

(33 citation statements)

References 6 publications

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“…Daun sirih merah atau Piper crocatum telah lama diketahui sebagai antiseptik tradisional yang sering digunakan oleh masyarakat Indonesia (Prabowo et al, 2018). Diketahui bahwa daun sirih merah mengandung senyawa-senyawa antibakteri seperti flavonoid, alkaloid senyawa polifenol, tanin dan minyak atsiri (Puspita et al, 2018). Flavonoid, alkaloid, tanin dan minyak atsiri pada daun sirih merah berfungsi sebagai zat aktif antibakteri diantaranya Staphylococcus aureus, Escherichia coli, dan Candida albicans (Candrasari et al, 2012).…”

Section: Pendahuluanunclassified

Peningkatan Pengetahuan tentang Pencegahan Infeksi dan Penyebaran Penularan COVID-19 di Panti Asuhan/LKSA Darul Tazkiyah Kota Palangka Raya

Purbayanti

Ardina

Suryadini

2021

Pengabdianmu J Ilmiah Pengabdian Masyarakat

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COVID-19 infection regardless of age. It can infect children, adults, and older adults. Children and older adults are high-risk groups of infection. An orphanage where many children live in one place with a high risk of transmission of the SARS-CoV-2 virus. Education about prevention of infection and the spread of COVID-19 transmission at Darul Tazkiyah orphanage Palangka Raya was needed. The implementation methods included a pre-test, education about COVID-19, post-test, and submission of calendars containing information on prevention of COVID-19, posters, betel leaf extract hand sanitizers and health protocols banners. A total of 46 orphanage children became respondents. The paired sample t-test showed that p-value (0.000) <0.05. It meant there was a difference between pre-test and post-test results, which meant there was an increasing children's knowledge about prevention of infection and the spread of COVID-19 transmission at Darul Tazkiyah Orphanage, Palangka Raya. Based on the results of the service activities carried out, it showed that providing education can increase children's knowledge about how efforts to prevent transmission of COVID-19, so it is hoped that this increased knowledge can minimize transmission of COVID-19 and help government programs to reduce positive cases of COVID-19 in Palangka Raya in particular.

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Section: Pendahuluanunclassified

Peningkatan Pengetahuan tentang Pencegahan Infeksi dan Penyebaran Penularan COVID-19 di Panti Asuhan/LKSA Darul Tazkiyah Kota Palangka Raya

Purbayanti

Ardina

Suryadini

2021

Pengabdianmu J Ilmiah Pengabdian Masyarakat

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“…By binding to fats and carbohydrates, terpenoids have adverse effects on the permeability of the bacterial cell membrane. 34 Biofilm susceptibility to antibacterial compounds is thought to be due to several factors, including the presence of extracellular polymeric substances surrounding bacterial cells. The antimicrobial agent is absorbed into the extracellular polymeric substances and is effectively diluted in its concentration before reaching individual cells in the biofilm.…”

Section: Discussionmentioning

confidence: 99%

Antimicrobial and Antibiofilm Activity of Cinnamon (Cinnamomum burmanii) Extract on Periodontal Pathogens—An in vitro study

et al. 2022

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Objective The aim of this study was to analyze the antibiofilm effectiveness of cinnamon (Cinnamomum burmanii) ethanol extract against Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans in vitro. Material and Methods Phytochemical tests were done to identify the cinnamon extract active substances. Furthermore, a crystal violet biofilm assay was used to analyze biofilm detachment after treatment with different concentrations (15, 10, 7.5, 5, and 2.5%) of cinnamon. Biofilm turbidity was measured at 595-nm wavelength using a microplate reader. Additionally, MTT assay was done to analyze the toxicity level of cinnamon extract on fibroblast cells. Statistical Analysis The obtained data were analyzed for normality using the Kolmogorov–Smirnov test. The differences between each group were analyzed using a one-way analysis of variance statistical test, with a significance level of p <0.05. Results The results showed that the ethanol extract of cinnamon contains active compounds of flavonoids, alkaloids, saponins, tannins, quinones, and terpenoids. MTT result showed the cinnamon extract to be nontoxic. The biofilm assay results showed that all cinnamon concentrations exhibited an antibiofilm effect against P. gingivalis and A. actinomycetemcomitans in all incubation time compared with a negative control (p <0.05). Conclusions Cinnamon extracts were effective in inhibiting biofilm of periodontal pathogens. Cinnamon extract might be useful as an alternative therapy for periodontal diseases. Future studies are still needed to confirm this result in vivo to analyze the efficacy of this extract as mouthwash.

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“… : Mengandung senyawa  : Tidak mengandung senyawa Uji fitokimia merupakan suatu pengujian yang bertujuan untuk mengetahui kandungan senyawa metabolit sekunder dari sutu cuplikan, Alkaloid adalah suatu senyawa yang mengandung satu atau lebih atom Nitrogen yang terbentuk dan biasanya terdapat dalam bentuk gabungan sebagai bagian dari sistem siklik [13]. Di dunia medis, alkaloid digunakan untuk menenangkan saraf pusat, menstimulasi kerja saraf, antibakteri, dan juga untuk terapi anti kanker [14].…”

Section: Keteranganunclassified

Skrining Fitokimia Ekstrak Daun Jeruk Lemon (Citrus limon L.) dari Kota Langsa, Aceh

Harahap

Halimatussakdiah

Amna

2021

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Telah dilakukan skrining fitokimia pada daun jeruk lemon. Jeruk lemon (Citrus limon L.) merupakan suatu tumbuhan yang sering dimanfaatkan oleh masyarakat terutama bagian buahnya. Untuk mengetahui kandungan kimianya, maka dilakukanlah uji keberadaan senyawa metabolit sekunder di dalam ekstrak daun jeruk lemon (Citrus limon L.). Daun jeruk lemon memiliki kandungan limonen yang dapat digunakan dalam terapi anti kanker. Ekstrak daun jeruk lemon diperoleh dengan menggunakan metode maserasi. Setelah ekstrak kasar daun jeruk lemon diperoleh, maka diuji kandungan senyawa fitokimianya secara kualitatif. Berdasarkan uji fitokimia yang dilakukan maka diketahui bahwa ekstrak daun jeruk lemon positif mengandung golongan senyawa alkaloid, flavonoid, fenol, dan tanin. Referensi : [1] A. W. Nugroho, “Konservasi Kenekaragaman Hayati Melalui Tanaman Obat Dalam Hutan di Indonesia Dengan Teknologi Farmasi: Potensi dan Tantangan,” J. Sains dan Kesehat., vol. 1, no. 7, pp. 377–383, 2017. [2] P. Setyaningrum, E. D., Kartika, R., Simanjuntak, “Uji Skrining Fitokimia dan Uji Aktivitas Antioksidan dari Daun Akasia (Acacia auriculiformkis Benth),” Pros. Semin. Nas. Kim., pp. 94–96, 2017. [3] M. Fitrah, “Identifikasi Ekstrak Daun Kopasanda (Chromolaena odorata Linn) Terhadap Sel Antiproliferasi Tikus Leukemia L1210,” Jf Fik Uinam, vol. 4, no. 3, pp. 99–105, 2016. [4] H. S. Indriani Y., Mulqie L., “Uji Aktivitas Antibakteri Air Perasan Buah Jeruk Lemon (Citrus limon (L.) Osbeck) dan Madu Hutan Terhadap Propionibacterium acne,” Pros. Penelit. Sivitas Akad. Unisba (Kesehatan dan Farm., vol. 2, no. 3, pp. 22–30, 2015. [5] E. Ahmad, F. M. Y., Katja, D. G., Suryanto, “Uji Fitokimia Ekstrak Kulit Batang Chisocheton sp.(C.DC) Harms Yang Tumbuh di Gunung Soputan Sulawesi Utara,” J. Ilm. Farm., vol. 7, no. 4, pp. 23–30, 2018. [6] W. Krisnawan, A. H., Budiono, R., Sari, D. R., Salim, “Potensi Antioksidan Ekstrak Kulit dan Perasan Daging Buah Lemon (Citrus limon) Lokal dan Import,” Pros. Semin. Nas., pp. 30–34, 2017. [7] P. Suja, D., G. Bupesh, N., Rajendiran, V., Mohan, P., Ramasamy, N. S.,Muthiah, A. A., Elizabeth, K., Meenakumari, K., “Phytochemical Screening, Antioxidant, Antibacterial Activities of Citrus Limon and Citrus Linensis Peel Extracts,” Int. J. Pharmacogn. Chinese Med., vol. 1, no. 2, p. 000108, 2017. [8] M. H. Yang, J. S. Wang, J. G. Luo, X. B. Wang, and L. Y. Kong, “Tetranortriterpenoids from Chisocheton paniculatus,” J. Nat. Prod., vol. 7, no. 2, pp. 36–43, 2009, doi: 10.1021/np900485t. [9] Badan POM RI, “Pedoman Teknologi Formulasi Sediaan Berbasis Ekstrak.Volume 2. Jakarta: Direktorat Obat Asli Indonesia, Deputi Bidang Pengawas Obat Tradisional, Kosmetik dan Produk Komplemen,” vol. 7, no. 8, pp. 12–16, 2013. [10] M. . T. Mayasari, U., Laoli, “Karakterisasi Simplisia dan Skrining Fitokimia Daun Jeruk Lemon (Citrus limon (L.) Burm. F.),” J. Ilmu Biol. dan Terap., vol. 2, no. 1, pp. 7–13, 2018. [11] A. Tuhuloula, L. Budiyarti, and E. N. Fitriana, “Karakterisasi Pektin dengan Memanfaatkan Limbah Kulit Pisang Menggunakan Metode Ekstraksi,” Konversi, vol. 2, no. 1, pp. 21–27, 2013, doi: 10.20527/k.v2i1.123. [12] H. Halimatussakdiah, U. Amna, and P. Wahyuningsih, “Preliminary Phytochemical Analysis and Larvicidal Activity of Edible Fern (Diplazium esculentum (Retz.) Sw.) Extract against Culex,” J. Nat., vol. 18, no. 3, pp. 141–146, 2018, doi: 10.24815/jn.v0i0.11335. [13] P. J. Puspita, M. Safithri, and N. P. Sugiharti, “Antibacterial Activities of Sirih Merah (Piper crocatum) Leaf Extracts,” Curr. Biochem., vol. 5, no. 3, pp. 1–10, 2019, doi: 10.29244/cb.5.3.1-10. [14] S. Susilawati and N. C. Chotimah, “Difference of Weight Gain in Baby Mother Given Boiled Of Papaya Fruit,” J. Kesehat., vol. 5, no. 1, pp. 34–39, 2019, doi: 10.25047/j-kes.v5i1.36. [15] R. Nugrahani, Y. Andayani, and A. Hakim, “Skrining Fitokimia dari Ekstrak Buah Buncis (Phaseolus vulgaris L) dalam Sediaan Serbuk,” J. Penelit. Pendidik. IPA, vol. 2, no. 1, pp. 96–103, 2016, doi: 10.29303/jppipa.v2i1.38. [16] M. H. Kemala, D., Hendiani, I., Satari, “Uji Daya Antibakteri Ekstrak Etanol Kulit Buah Manggis (Garciani mangostana L) Terhadap Streptococcus Sanguinis ATCC 10556,” Padjajaran J. Dent. Res. Students, vol. 3, no. 1, pp. 1–5, 2019. [17] M. Syafrida, S. Darmanti, and M. Izzati, “Pengaruh Suhu Pengeringan Terhadap Kadar Air, Kadar Flavonoid dan Aktivitas Antioksidan Daun dan Umbi Rumput Teki (Cyperus rotundus L.),” Bioma Berk. Ilm. Biol., vol. 20, no. 1, pp. 44–50, 2018, doi: 10.14710/bioma.20.1.44-50. [18] S. W. Azizah, Z., zulharmita., wati, “Skrining Fitokimia dan Penetapan Kadar Flavonoid Total Ekstrak Daun Pre (Momordica charantia L.),” J. Farm. Higea, vol. 10, no. 2, pp. 163–172, 2018. [19] N. Hidayah, “Pemanfaatan Senyawa Metabolit Sekunder Tanaman (Tanin dan Saponin) dalam Mengurangi Emisi Metan Ternak Ruminansia,” J. Sain Peternak. Indones., vol. 1, no. 2, pp. 89–98, 2016, doi: 10.31186/jspi.id.11.2.89-98. [20] H. Nurjannati, M., Winarsi, H., dan Dwiyanti, “Efek Lama Perkecambahan Terhadap Sifat Sensori dari Kadar Protein Terlarut Susu Kecambah Kacang Merah (Sukarah) untuk Remaja Obesitas,” J. Gipas, vol. 2, no. 2, pp. 27–42, 2018. [21] Sarifudin, A., Wardatun, S., “Kajian Metode Pengeringan dan Metode Analisis Daun Belimbing Wuluh (Averrhoa bilimbi L.) Terhadap Kadar Tanin,” J. Online Mhs. Bid. Farm., vol. 1, no. 1, pp. 1–9, 2015. [22] S. Noer and R. D. Pratiwi, “Uji Kualitatif Fitokimia Daun Ruta Angustifola,” Fakt. Exacta, vol. 9, no. 3, pp. 200–206, 2016.

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Antibacterial Activities of Sirih Merah (<i>Piper crocatum</i>) Leaf Extracts

Cited by 25 publications

References 6 publications

Peningkatan Pengetahuan tentang Pencegahan Infeksi dan Penyebaran Penularan COVID-19 di Panti Asuhan/LKSA Darul Tazkiyah Kota Palangka Raya

Peningkatan Pengetahuan tentang Pencegahan Infeksi dan Penyebaran Penularan COVID-19 di Panti Asuhan/LKSA Darul Tazkiyah Kota Palangka Raya

Antimicrobial and Antibiofilm Activity of Cinnamon (Cinnamomum burmanii) Extract on Periodontal Pathogens—An in vitro study

Skrining Fitokimia Ekstrak Daun Jeruk Lemon (Citrus limon L.) dari Kota Langsa, Aceh

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