Antibiotic protocol for the prevention of osteoradionecrosis following dental extractions in irradiated head and neck cancer patients: A 10 years prospective study

Al-Bazie, Saleh A; Bahatheq, M.; Al-Ghazi, Mohamad; Al-Rajhi, Nasser; Ramalingam, Sundar

doi:10.4103/0973-1482.159090

Cited by 22 publications

(35 citation statements)

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“…4 Quando as exodontias são realizadas após a radioterapia, diversas medidas são propostas para diminuir a ocorrência da ORN, entre elas o uso da pentoxifilina associada ao tocoferol, oxigênio hiperbárico e antibioticoterapia. 2,6,10 A pentoxifilina induz a dilatação vascular e o aumento da flexibilidade dos eritrócitos, resultando em aumento do fluxo sanguíneo. 6,7 O tocoferol é uma vitamina solúvel em gordura e fraco agente antioxidante, sendo portanto capaz de eliminar as espécies que reagem ao oxigênio, envolvidas no desenvolvimento da ORN.…”

Section: Discussionunclassified

Osteorradionecrose em mandíbula tratada com fibrina rica em plaquetas e bola de Bichat: relato de caso clínico

Milani¹,

Pereira²,

Melzer³

et al. 2019

j.rpemd

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On-line a 27 de agosto de 2019 A osteorradionecrose é uma complicação oral severa que pode afetar pacientes submetidos à radioterapia de cabeça e pescoço. É definida como uma área de osso irradiado e exposto, que não cicatriza em um período de três meses, sem tumor residual ou recidivante. Os aspetos radiológicos são inespecíficos, aparecendo como áreas radiotransparentes, com sequestros ósseos, lembrando uma osteomielite ou osteonecrose associada a medicamento. O diagnóstico é obtido através da associação dos dados clínicos e imagiológicos. Não há um protocolo definido para o tratamento, podendo o mesmo ser conservador ou cirúrgico. O objetivo deste estudo foi apresentar um caso de osteorradionecrose tratado com a remoção do sequestro ósseo e enxerto de fibrina rica em plaquetas e bola de Bichat, em uma paciente do género feminino, de 63 anos. (Rev Port Estomatol

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Section: Discussionunclassified

Osteorradionecrose em mandíbula tratada com fibrina rica em plaquetas e bola de Bichat: relato de caso clínico

Milani¹,

Pereira²,

Melzer³

et al. 2019

j.rpemd

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“…[ 9 ] While several diseases involving the cardiovascular, endocrine, hepatorenal, immune and neurological systems have been reported as relative contraindications, disorders of bone due to osteoporosis, bisphosphonate treatment, and exposure to ionizing radiation have been reported as the worst contraindications for dental implant survival. [ 6 10 12 17 18 ] More importantly, the level of control of the medical problem has been regarded as the key indicator for dental implant success among medically compromised dental patients. [ 1 2 4 ]…”

Section: Discussionmentioning

confidence: 99%

Perceptions of dental interns in Saudi Arabia toward implant placement in medically compromised patients

Ramalingam

Habib

Sundar

et al. 2017

J Edu Health Promot

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BACKGROUND AND AIM:Increasing incidence of medically compromised patients seeking dental treatment and implant rehabilitation, necessitates greater knowledge toward managing such patients. The objective of the present study was to evaluate the perceptions of dental interns in Riyadh, Saudi Arabia, toward dental implant therapy for medically compromised patients.MATERIALS AND METHODS:Using a convenience random sampling technique, a cross-sectional questionnaire-based study was conducted to evaluate the perceptions of the interns from dental schools in Riyadh, Saudi Arabia. Data pertaining to demographic details of the participants, academic grade point average (GPA), clinical implant training and experience and perceptions about dental implant therapy for medically compromised patients were collected.RESULTS:The survey response rate was 82.9% (n = 174/210; Males-129/Females-45). Less than half of the interns (n = 82/174; 47.1%) had performed dental implants, out of which 41.5% (n = 34/82) had placed implants in medically compromised patients. Most medical illnesses except controlled diabetes mellitus and hypertension were perceived by the interns as contraindications for dental implant placement.CONCLUSION:Based on the results of the present study, it could be concluded that courses with a greater emphasis toward management of dental patients with medical problems and undergraduate implant training for such patients would result in better knowledge and perception among dental interns regarding dental implant placement in medically compromised patients.

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“…Moreover, the use of microbiological identification tests in order to determine the species involved may help in cases requiring long duration of treatment. Therefore, the use of pre‐ and post‐extraction antibiotics and mouthwashes with chlorhexidine show efficiency to prevent ORN in patients who have undergone irradiation in the regions of the head and neck.…”

Section: Discussionmentioning

confidence: 99%

Success of preventive approach to mandibular osteoradionecrosis in an adolescent: case report.

et al. 2017

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Osteoradionecrosis (ORN) is defined as the presence of ulceration or necrosis of the mucosa with exposure of necrotic bone that does not heal within a 2-month period after radiotherapy in patients with head and neck tumours. The mandible presents a higher risk of developing ORN than the maxilla and extraction of teeth is also considered a risk factor for the development of ORN. The aim of this article was to present a clinical case where a protocol was used to prevent the development of ORN after the extraction of lower molars in an adolescent who had undergone surgical removal and radiotherapy for a mucoepidermoid carcinoma in the left parotid gland. The results showed that the protocol used was efficient in the prevention of osteoradionecrosis in this adolescent. One year after the extractions, no clinical or radiographic signs of any pathological alteration were observed in the region; the patient remains under periodical clinical and radiographic follow-up.Oral Surgery 10 (2017) e104--e109.

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Antibiotic protocol for the prevention of osteoradionecrosis following dental extractions in irradiated head and neck cancer patients: A 10 years prospective study

Abstract: Based on the results of this study, perioperative oral antibiotics in combination with antibacterial mouthwashes are effective in preventing ORN following dental extractions in irradiated patients.

Cited by 22 publications

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Osteorradionecrose em mandíbula tratada com fibrina rica em plaquetas e bola de Bichat: relato de caso clínico

Osteorradionecrose em mandíbula tratada com fibrina rica em plaquetas e bola de Bichat: relato de caso clínico

Perceptions of dental interns in Saudi Arabia toward implant placement in medically compromised patients

Success of preventive approach to mandibular osteoradionecrosis in an adolescent: case report.

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