Application of calcium phosphatenanoparticles in biomedicine

Calcium Phosphate Scaffold Loaded with Platinum Nanoparticles for Bone Allograft

“…However, these approaches have their drawbacks, such as the need for second surgery at the donor site, limited quantity and shape of available bone, and resorption of the bone graft (4)(5). A range of porous materials, such as ceramics, polymers and metals have been developed in the field of bone grafts and scaffolds for tissue engineering (2)(3)(4)(5)(6)(7)(8)(9)(10). Some of the most favourable bioactive ceramic materials that were used in bone grafting and tissue engineering are calcium phosphate due to their exceptional physical and chemical properties (2,(4)(5).…”

“…However, their poor mechanical properties, in particular their toughness, is a significant problem Successful incorporation of calcium phosphate with polymers has been achieved for the fabrication of scaffolds that have good porosity, degradability and protein absorption, while accomplishing acceptable mechanical properties in term of toughness (7)(8). These scaffolds were subsequently used as an alternative autologous bone graft for tissue engineering (8)(9). Generally, tissue engineering scaffolds should have suitable pore area micro-pore size, degradability and good mechanical properties (10) .…”

“…Generally, tissue engineering scaffolds should have suitable pore area micro-pore size, degradability and good mechanical properties (10) . Thereby, designing a scaffold material from ceramics with other materials such as metals or polymers may lead to good simulation of the structure and properties of tissues to be replaced, and offers a tremendous potential for solving these problems (9)(10).…”

Моделирование И Анализ Данных Синхроторонного Облучения Для Модифицированной Структуры Гидроксиапатита

“…The main usage area is HAP coating on bone and dental implants to modify their surface properties for the best osseointegration [1,2]. Biological HAP differs from the mineral one: it consists of many deviations such as non stoichiometry content, replacements, vacancies and other defects.…”

“…Hydroxyapatite (HAP) is one of the most demanded materials in implantology of bones and teeth [1][2][3][4][5]. The main usage area is HAP coating on bone and dental implants to modify their surface properties for the best osseointegration [1,2].…”