Au nanoparticles stabilised by PEGylated low generation PAMAM dendrimers: Design, characterisation and properties

Dietrich, Sascha; Schulze, Steffen; Hietschold, Michael; Lang, Heinrich

doi:10.1016/j.jcis.2011.03.092

Cited by 18 publications

(9 citation statements)

References 109 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The XPS image of AuNPs/GG1PD has a splitting ratio difference of 1.12 eV. C 1s spectra of GG1PD (Figure d) and AuNPs/GG1PD (Figure e) indicate that binding energies of different carbons are observed at 284.5 eV (graphitic CC species), 285.3 eV (C–C), 286.25 eV (C–N), and 288.0 eV (N–CO). , GG1PD decorated with AuNPs shows lower peak intensities and increased atomic percentages (Figure e). , It may be noted that the single layer of graphene on the Au-coated substrate has a binding energy of 284.4 eV, and the suspended single layer graphene has a higher binding energy of 284.8 eV . The C 1s peak of GG1PD is observed at 284.4 eV, which is lower than that of GG1PD–AuNPs observed at 284.8 eV.…”

Section: Resultsmentioning

confidence: 95%

“…Tang et al designed a AuNPs-decorated PD, which provided biocompatible immobilization and a promising immunosensing platform for highly sensitive electrochemical analysis of small molecules and the detection of food safety . Dietrich et al mentioned that G2PD could control the size of AuNPs better, leading to excellent catalytic activity and stable structure, thereby enhancing biosensing performance …”

Section: Introductionmentioning

confidence: 99%

“…22 Dietrich et al mentioned that G2PD could control the size of AuNPs better, leading to excellent catalytic activity and stable structure, thereby enhancing biosensing performance. 23 In this work, we focused on the construction, characterization, and optimization of a controllable 3D nanoarchitecture based on layer-by-layer (LBL)-assembled AuNPs-decorated first-generation (G1) PD with reduced graphene oxide (rGO) as core covalently functionalized with mercaptopropinoic acid (MPA) self-assembled nanolayer onto the surface of gold (Au) substrate (Scheme 1), which was employed as highly sensitive and label-free nanobiosensing platform for the rapid DPV analysis of DNA hybridization at ultratrace levels. This study will focus on the controllable fabrication of open and porous structure through LBL-assembled methods and the characterization of controllable 3D nanoachitecture based on G1PD with a nanomaterial as core. ]…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Layer-by-Layer-Assembled AuNPs-Decorated First-Generation Poly(amidoamine) Dendrimer with Reduced Graphene Oxide Core as Highly Sensitive Biosensing Platform with Controllable 3D Nanoarchitecture for Rapid Voltammetric Analysis of Ultratrace DNA Hybridization

Jayakumar

Camarada

Dharuman

et al. 2018

ACS Appl. Mater. Interfaces

View full text Add to dashboard Cite

The structure and electrochemical properties of layer-by-layer-assembled gold nanoparticles (AuNPs)-decorated first-generation (G1) poly(amidoamine) dendrimer (PD) with reduced graphene oxide (rGO) core as a highly sensitive and label-free biosensing platform with a controllable three-dimensional (3D) nanoarchitecture for the rapid voltammetric analysis of DNA hybridization at ultratrace levels were characterized. Mercaptopropinoic acid (MPA) was self-assembled onto Au substrate, then GG1PD formed by the covalent functionalization between the amino terminals of G1PD and carboxyl terminals of rGO was covalently linked onto MPA, and finally AuNPs were decorated onto GG1PD by strong physicochemical interaction between AuNPs and -OH of rGO in GG1PD, which was characterized through different techniques and confirmed by computational calculation. This 3D controllable thin-film electrode was optimized and evaluated using [Fe(CN)] as the redox probe and employed to covalently immobilize thiol-functionalized single-stranded DNA as biorecognition element to form the DNA nanobiosensor, which achieved fast, ultrasensitive, and high-selective differential pulse voltammetric analysis of DNA hybridization in a linear range from 1 × 10 to 1 × 10 g m with a low detection limit of 9.07 × 10 g m. This work will open a new pathway for the controllable 3D nanoarchitecture of the layer-by-layer-assembled metal nanoparticles-functionalized lower-generation PD with two-dimensional layered nanomaterials as cores that can be employed as ultrasensitive and label-free nanobiodevices for the fast diagnosis of specific genome diseases in the field of biomedicine.

show abstract

Section: Resultsmentioning

confidence: 95%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Layer-by-Layer-Assembled AuNPs-Decorated First-Generation Poly(amidoamine) Dendrimer with Reduced Graphene Oxide Core as Highly Sensitive Biosensing Platform with Controllable 3D Nanoarchitecture for Rapid Voltammetric Analysis of Ultratrace DNA Hybridization

Jayakumar

Camarada

Dharuman

et al. 2018

ACS Appl. Mater. Interfaces

View full text Add to dashboard Cite

show abstract

“…The poly(ethyleneglycol)-poly(amidoamine) dendrimers were synthesized [9,10] and used to stabilize and functionalize the magnetic nanoparticles. One of the dendrimers had 6 long dendritic arms (L6-PEG-PAMAM) and the other dendrimer had 6 comparatively short arms (S6-PEG-PAMAM) (Fig.…”

Section: Materials Usedmentioning

confidence: 99%

Dendrimer-magnetic nanoparticles as multiple stimuli responsive and enzymatic drug delivery vehicle

Chandra

Noronha

Dietrich

et al. 2015

Journal of Magnetism and Magnetic Materials

Self Cite

View full text Add to dashboard Cite

“…It has been proven by various studies that anchoring metal NP's on supports is an effective approach to solve the aggregation problem. Therefore, many materials have been designed for the stabilization of metal NP's, such as surfactants 6 , micelles 7 , microspheres 8 , hollow capsules 9 , polymer brushes 10 , polymer microgels 11 and dendrimers 12 . Of the wide range of materials, polymer microgels have attracted considerable interest due to their high surface area and quick responsive behavior towards environmental stimuli.…”

Section: Introductionmentioning

confidence: 99%

Responsive Polymer Hybrid Gel Cross-Linked by N,n-(1,2-Dihydroxyethylene) Bisacrylamide for Catalytic Application

Iqbal

Shah

Sayed

et al. 2016

J. Chil. Chem. Soc.

View full text Add to dashboard Cite

Copolymer microgel composed of N-isopropyl acrylamide and methacrylic acid, poly(NIPAM-MAA), was synthesized by free radical emulsion polymerization using N,N-(1,2-dihydroxyethylene) bisacrylamide as cross-linking agent. The hybrid microgels poly(NIPAM-MAA)-Au and poly(NIPAM-MAA)-Ag, were synthesized by in-situ reduction of metal ions using sodium borohydride (NaBH 4 ) as reducing agent. The temperature and pH sensitivity of pure and hybrid microgels were studied by dynamic light scattering (DLS) and UV-Visible spectroscopy. The existence of gold and silver nanoparticles inside the microgel network was confirmed by transmission electron microscopy (TEM). Poly(NIPAM-MAA)-Au and poly(NIPAM-MAA)-Ag hybrid microgels were tested for the comparative catalytic activity towards the reduction of 4-nitrophenol to 4-aminophenol. The apparent rate constant (k app ) for poly(NIPAM-MAA)-Au was found superior than poly(NIPAM-MAA)-Ag. Keywords:Free radical emulsion polymerization, in-situ reduction method, hybrid microgels, surface plasmon resonance, catalytic activity . However, the enhanced surface energy causes aggregation of these NP's and hinders their applications in many fields. INTRODUCTIONIn recent decades, many attempts have been made to overcome this problem. It has been proven by various studies that anchoring metal NP's on supports is an effective approach to solve the aggregation problem. Therefore, many materials have been designed for the stabilization of metal NP's, such as surfactants 6 , micelles 7 , microspheres 8 , hollow capsules 9 , polymer brushes 10 , polymer microgels 11 and dendrimers 12 . Of the wide range of materials, polymer microgels have attracted considerable interest due to their high surface area and quick responsive behavior towards environmental stimuli. Agrawal et al 13 prepared N-vinylcaprolactam/acetoacetoxyethyl methacrylate/acrylic acid microgels for the entrapment of colloidal gold nanostructure and studied their catalytic properties. Zheng et al 14 synthesized chitosan and acrylic acid based granular hydrogels for the stabilization of silver nanoparticles and used it for the catalytic reduction of organic dyes. We have successfully fabricated silver nanoparticles inside the pure thermo responsive poly(N-isopropyl acrylamide) microgels synthesized with different crosslinking density 15 and dual responsive cationic poly(N-isopropyl acrylamide-co-vinylimidazole) microgels 16 . The hybrid microgels were used as a catalyst for the reduction of 4-nitrophenol at entire pH range and the catalyst was found more efficient at pH < 6. In all these studies N, N-methylene bisacrylamide used as a crosslinking agent. To best of our knowledge very little work has been done using N,N-(1,2-Dihydroxyethylene) bisacrylamide (DHEBA) as cross linking moiety 17 for 3D microgel formation and used as a templet for immobilization of metal nanoparticles.In this work we have carried out the synthesis of stable poly(NIPAM-MAA) microgels has been explored by using DHEBA as cross-linker for the fabrication ...

show abstract

Au nanoparticles stabilised by PEGylated low generation PAMAM dendrimers: Design, characterisation and properties

Cited by 18 publications

References 109 publications

Layer-by-Layer-Assembled AuNPs-Decorated First-Generation Poly(amidoamine) Dendrimer with Reduced Graphene Oxide Core as Highly Sensitive Biosensing Platform with Controllable 3D Nanoarchitecture for Rapid Voltammetric Analysis of Ultratrace DNA Hybridization

Layer-by-Layer-Assembled AuNPs-Decorated First-Generation Poly(amidoamine) Dendrimer with Reduced Graphene Oxide Core as Highly Sensitive Biosensing Platform with Controllable 3D Nanoarchitecture for Rapid Voltammetric Analysis of Ultratrace DNA Hybridization

Dendrimer-magnetic nanoparticles as multiple stimuli responsive and enzymatic drug delivery vehicle

Responsive Polymer Hybrid Gel Cross-Linked by N,n-(1,2-Dihydroxyethylene) Bisacrylamide for Catalytic Application

Contact Info

Product

Resources

About