Biotransformation of aflatoxin B1 and aflatoxin G1 in peanut meal by anaerobic solid fermentation of Streptococcus thermophilus and Lactobacillus delbrueckii subsp. bulgaricus

Chen, Yujie; Kong, Qing; Chen, Chi; Shan, Shiguang; Guan, Bin

doi:10.1016/j.ijfoodmicro.2015.06.021

Cited by 42 publications

(20 citation statements)

References 31 publications

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“…One of the essential considerations at this stage is to validate the detoxification activity of MBMs in the complex food/feed matrices to which they will be applied, such as corn, wheat, barley, DGGS, peanut meal, pistachio nut, rice straw, apple juice, apple puree and grape must [13,20,32,37,38,39,47,53,54,100,108,110,167]. The typical procedure includes preparation of samples with either spiked or naturally-contaminated mycotoxins, incubation of samples with the MBMs under natural conditions, followed by extraction and chemical analysis of mycotoxins and their metabolites.…”

Section: Strategies and Methodologiesmentioning

confidence: 99%

Strategies and Methodologies for Developing Microbial Detoxification Systems to Mitigate Mycotoxins

Zhu

Hassan

Lepp

et al. 2017

Toxins

100

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Mycotoxins, the secondary metabolites of mycotoxigenic fungi, have been found in almost all agricultural commodities worldwide, causing enormous economic losses in livestock production and severe human health problems. Compared to traditional physical adsorption and chemical reactions, interest in biological detoxification methods that are environmentally sound, safe and highly efficient has seen a significant increase in recent years. However, researchers in this field have been facing tremendous unexpected challenges and are eager to find solutions. This review summarizes and assesses the research strategies and methodologies in each phase of the development of microbiological solutions for mycotoxin mitigation. These include screening of functional microbial consortia from natural samples, isolation and identification of single colonies with biotransformation activity, investigation of the physiological characteristics of isolated strains, identification and assessment of the toxicities of biotransformation products, purification of functional enzymes and the application of mycotoxin decontamination to feed/food production. A full understanding and appropriate application of this tool box should be helpful towards the development of novel microbiological solutions on mycotoxin detoxification.

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Section: Strategies and Methodologiesmentioning

confidence: 99%

Strategies and Methodologies for Developing Microbial Detoxification Systems to Mitigate Mycotoxins

Zhu

Hassan

Lepp

et al. 2017

Toxins

100

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“…AFB 2 a is 200 times less toxic than AFB 1 and is considered to be relatively non-toxic. AFD 1 was found to be non-toxic based on in vitro toxicity studies using Hela cells [ 87 , 231 , 232 ].…”

Section: Rumen Microbial Detoxification Of Mycotoxinsmentioning

confidence: 99%

Toxin Degradation by Rumen Microorganisms: A Review

Loh

Ouwerkerk

Klieve

et al. 2020

Toxins

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Animal feeds may contain exogenous compounds that can induce toxicity when ruminants ingest them. These toxins are secondary metabolites originating from various sources including plants, bacteria, algae and fungi. Animal feed toxins are responsible for various animal poisonings which negatively impact the livestock industry. Poisoning is more frequently reported in newly exposed, naïve ruminants while ‘experienced’ ruminants are observed to better tolerate toxin-contaminated feed. Ruminants can possess detoxification ability through rumen microorganisms with the rumen microbiome able to adapt to utilise toxic secondary metabolites. The ability of rumen microorganisms to metabolise these toxins has been used as a basis for the development of preventative probiotics to confer resistance against the poisoning to naïve ruminants. In this review, detoxification of various toxins, which include plant toxins, cyanobacteria toxins and plant-associated fungal mycotoxins, by rumen microorganisms is discussed. The review will include clinical studies of the animal poisoning caused by these toxins, the toxin mechanism of action, toxin degradation by rumen microorganisms, reported and hypothesised detoxification mechanisms and identified toxin metabolites with their toxicity compared to their parent toxin. This review highlights the commercial potential of rumen inoculum derived probiotics as viable means of improving ruminant health and production.

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“…Firstly, Farzaneh et al (2012) demonstrated 95% AFB1 degradation by Bacillus subtilis UTBSP1 on shell nuts. Secondly, Chen et al (2015) showed 100% AFB1 removal by the mixed treatment of L. delbrueckii subsp. Bulgaricus and Streptococcus thermophilus on pistachios nuts.…”

Section: Physical and Chemical Reductionsmentioning

confidence: 96%

Microbial degradation of aflatoxin B1: Current status and future advances

Verheecke‐Vaessen

Liboz

Mathieu

2016

International Journal of Food Microbiology

115

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Aflatoxin B1 (AFB1) is a natural toxin produced by many food-contaminant fungi and is a threat to human and animal health. This review summarizes current knowledge of the different ways to limit AFB1 in the food chain. We start by introducing current data and reviews available on the prevention of AFB1 occurrence, on AFB1 non-biological decontamination and biological adsorption. We then focus on microbial AFB1-degradation. The latter has already been well studied using living organisms, supernatants or purified enzymes. This review compiles information on the variety of protocols and the efficacy of the different sub-kingdoms or classes of microorganisms or their enzymes. We pay particular attention to publications closest to in vivo applications of microbial AFB1-degradation. In addition, this review also provides a summary of the currently known microbial degradation metabolites of AFB1 and their levels of toxicity, and provides recommendations on the most promising techniques to pursue the aim of minimizing ABF1 in the food supply.

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Biotransformation of aflatoxin B1 and aflatoxin G1 in peanut meal by anaerobic solid fermentation of Streptococcus thermophilus and Lactobacillus delbrueckii subsp. bulgaricus

Cited by 42 publications

References 31 publications

Strategies and Methodologies for Developing Microbial Detoxification Systems to Mitigate Mycotoxins

Strategies and Methodologies for Developing Microbial Detoxification Systems to Mitigate Mycotoxins

Toxin Degradation by Rumen Microorganisms: A Review

Microbial degradation of aflatoxin B1: Current status and future advances

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