Changes in crystal types of low solubility calcium phosphates in the presence of accompanying ions

Newesely, H

doi:10.1016/0003-9969(61)90032-2

Cited by 71 publications

(21 citation statements)

References 4 publications

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“…The Te-CP was produced by heating a compacted, equimolar mixture of calcium carbonate and anhydrous DCP at 1500°C for a total of 12 h. The mixture was preheated at 1500°C for 6 h and powdered for the second heating before compaction. The OCP was prepared by the homogeneous precipitation method of Newesely 22 at 60°C. One liter of 80 mmol calcium chloride solution buffered to pH 5.85 with 200 mmol of sodium acetate was gently poured into 1 L of 60 mmol disodium phosphate dihydrate solution buffered to pH 5.85 with 200 mmol of sodium acetate at room temperature.…”

Section: Calcium Phosphatesmentioning

confidence: 99%

Osteoclastic responses to various calcium phosphates in cell cultures

Doi

Iwanaga

Sendo

et al. 1999

J. Biomed. Mater. Res.

180

126

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Disks made of hydroxyapatite, beta-tricalcium phosphate, carbonate apatite, tetracalcium phosphate, alpha-tricalcium phosphate, dicalcium phosphate dihydrate, and octacalcium phosphate were incubated in osteoclastic cell cultures for 2 days. The first five salts were sintered and the last two were compressed before incubation. Osteoclasts resorbed only the sintered carbonate apatite disks. However, osteoclasts were able to resorb octacalcium phosphate disks that were preincubated for 1 day in medium without cells, indicating that surface conditioning was important for osteoclastic resorption of this calcium phosphate. Although resorption did not occur, medium calcium and phosphorus changed to an appreciable extent after a 2-day incubation of beta-tricalcium phosphate, tetracalcium phosphate, alpha-tricalcium phosphate, and dicalcium phosphate dihydrate. These changes in the medium calcium and phosphate concentrations could explain why osteoclasts appeared to have lost their activity on these calcium phosphate disks and were not capable of resorbing them. With hydroxyapatite disks no changes were observed in the medium calcium and phosphorus before and after incubation. Moreover, the osteoclasts appeared to be essentially the same as with the sintered carbonate apatite disks and with bone slices used as a control. Nevertheless, no pits or lacunae were observed on the hydroxyapatite disks, indicating that sintered carbonate apatite should be superior to sintered hydroxyapatite as a bioresorbable bone substitute.

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Section: Calcium Phosphatesmentioning

confidence: 99%

Osteoclastic responses to various calcium phosphates in cell cultures

Doi

Iwanaga

Sendo

et al. 1999

J. Biomed. Mater. Res.

180

126

View full text Add to dashboard Cite

show abstract

“…Several authors believed it to be identical in composition to other calcium phosphates, notably brushite (DCPD) (2), octacalcium phosphate (OCP) (3), and tricalcium phosphate (TCP) (6)(7)(8). However, more recent work by Termine and Eanes (9) indicated that the chemical composition of ACP is pH-dependent and that at most short-range order is to be expected.…”

Section: Introductionmentioning

confidence: 97%

Light scattering studies on solutions containing calcium phosphates

Feenstra¹,

Bruyn²

1980

Journal of Colloid and Interface Science

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“…It has been reported [Newesely, 1961], for example, that the rate of precipitation of calcium hydroxyapatite (HA) is greatly accelerated by very small concentrations of fluoride. Whether this is due to an acceleration in the conversion of possible apatite precursors or to the forma tion of more effective seeds for crystal growth is not clear at present.…”

Section: Introductionmentioning

confidence: 99%