Changes in the mechanical properties, biochemical contents and wall structure of the human coronary arteries with age and sex

Ozolanta, Iveta; Tetere, G.; Purinya, B. A.; Kasyanov, Vladimir

doi:10.1016/s1350-4533(98)00050-2

Cited by 97 publications

(85 citation statements)

References 22 publications

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“…For the rest, the elbow stress is close to the working stress of the artery. These observations are coherent with published in vivo studies of aortic distensibility, which show a fall in arterial compliance with age [12]. Data on the wall distensibility could be used in the selection of the bypass graft in order to reduce the mechanical mismatch and therefore the stresses at the anastomosis.…”

Section: B Evaluation Of the Mechanical Parameterssupporting

confidence: 88%

“…Only a few studies [10]- [18] have tried to characterize the in vivo behavior of human coronaries through in vivo and in vitro tests under physiological conditions. Maybe the most complete in-vitro work has been carried out by Ozolanta et al [12]; they studied in 205 patients the evolution with age of distensibility and modulus of elasticity of coronary arteries in the 0-240 mmHg pressure range. Similar research was performed by Williams et al [10] (in-vivo) and Tajaddini et al [11] (in-vitro), which showed -in agreement with Ozolanta et al [12]-that distensibility decreases and the modulus of elasticity increases with age.…”

Section: Introductionmentioning

confidence: 99%

“…Maybe the most complete in-vitro work has been carried out by Ozolanta et al [12]; they studied in 205 patients the evolution with age of distensibility and modulus of elasticity of coronary arteries in the 0-240 mmHg pressure range. Similar research was performed by Williams et al [10] (in-vivo) and Tajaddini et al [11] (in-vitro), which showed -in agreement with Ozolanta et al [12]-that distensibility decreases and the modulus of elasticity increases with age. To the authors' knowledge, most of the mechanical studies on human coronary arteries in the literature have been limited to compliance and stiffness measurements not beyond twice or three times physiological pressure.…”

Section: Introductionmentioning

confidence: 99%

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Mechanical properties of human coronary arteries

Claes

Atienza

Guinea

et al. 2010

2010 Annual International Conference of the IEEE Engineering in Medicine and Biology

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Abstract-The lack of reliable mechanical data on coronary arteries and, more specifically, on their wall strength hampers the application of numerical models and simulations to vascular problems, and precludes physicians from knowing in advance the response of coronary arteries to the different interventions. Studies of the mechanical properties of coronary arteries have been carried out almost exclusively on animals. Only a few studies have tried to characterize the in vivo behavior of human coronaries through tests under physiological conditions. In this work, the mechanical properties of human coronary arteries have been characterized. Whole samples from human right (RC) and left anterior descending (LAD) coronary arteries aged between 23 and 83 years have been studied by means of in-vitro tensile testing up to failure.

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Section: B Evaluation Of the Mechanical Parameterssupporting

confidence: 88%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Mechanical properties of human coronary arteries

Claes

Atienza

Guinea

et al. 2010

2010 Annual International Conference of the IEEE Engineering in Medicine and Biology

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“…Through a combination of layers of varying structure is formed tissue to withstand large compressive and shear stress to protect the elements of the movement. The stiffness of cartilage evaluated using a summary module is in the range of from 0.5 to 0.9 MPa [6,12]. At equilibrium, Young's modulus has a value from 0.45 to 0.8 MPa [6].…”

Section: Biomechanics Of Articular Cartilagementioning

confidence: 99%

Structural Analysis of Articular Cartilage of the Hip Joint Using Finite Element Method

Karpiński¹,

Jaworski²,

Zubrzycki³

2016

Adv. Sci. Technol. Res. J.

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The paper presents the results of a preliminary study on the structural analysis of the hip joint, taking into account changes in the mechanical properties of the articular cartilage of the joint. Studies have been made due to the need to determine the tension distribution occurring in the cartilage of the human hip. These distribution are the starting point for designing custom made human hip prosthesis. Basic anatomy, biomechanical analysis of the hip joint and articular cartilage are introduced. The mechanical analysis of the hip joint model is conducted. Final results of analysis are presented. Main conclusions of the study are: the capability of absorbing loads by articular cartilage of the hip joint is preliminary determined as decreasing with increasing degenerations of the cartilage and with age of a patient. Without further information on changes of cartilage's mechanical parameters in time it is hard to determine the nature of relation between mentioned capability and these parameters.

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“…Physiological h/D ext for coronary arteries have been extensively studied: for instance, [21] reported values between 0.08 and 0.44 depending on the age of the subject and the artery (left coronary artery vs right coronary artery).…”

Section: Analytical Solution In a "Semi-infinite" Tubementioning

confidence: 99%

Implementing Boundary Conditions in Simulations of Arterial Flows

Bokov¹,

Flaud

Bensalah

et al. 2013

Journal of Biomechanical Engineering

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Computational hemodynamic models of the cardiovascular system are often limited to finite segments of the system and therefore need well-controlled inlet and outlet boundary conditions. Classical boundary conditions are measured total pressure or flow rate imposed at inlet and impedances of RLR, RLC or LR filters at outlet. We present a new approach based on a unidirectional propagative hypothesis (UPH) to model the inlet/outlet boundary conditions on the axisymmetric Navier-Stokes equations. This condition is equivalent to a non-reflecting boundary condition in a fluid-structure interaction model of an axisymmetric artery. First we compare the UPH to the best impedance filter (RLC). Second, we apply this approach to a physiological situation i.e. the presence of a stented segment into a coronary artery. In that case a reflection index is defined which quantifies the amount of pressure waves reflected upon the singularity.

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Changes in the mechanical properties, biochemical contents and wall structure of the human coronary arteries with age and sex

Cited by 97 publications

References 22 publications

Mechanical properties of human coronary arteries

Mechanical properties of human coronary arteries

Structural Analysis of Articular Cartilage of the Hip Joint Using Finite Element Method

Implementing Boundary Conditions in Simulations of Arterial Flows

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