Chlamydia pneumoniae sero-prevalence in Moroccan patients with cardiovascular diseases

Radouani, Fouzia; Yazouli, Loubna El; Elyazghi, Zakaria; Hejaji, Hicham; Alami, A.; Elmdaghri, Naima

doi:10.1016/j.idh.2018.10.004

Cited by 5 publications

(4 citation statements)

References 29 publications

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“…Secondly, it may be used to differentiate between various immunoprofiles. Lastly, comparative studies show that immunoblotting has a similar or even better specificity and sensitivity than MIF [55]. One important point is that surface proteins of Cp are not diagnostically reliable [56].…”

Section: Chlamydia Pneumoniaementioning

confidence: 99%

Diagnostics of atypical pulmonary infections

Adamczyk¹,

Parkolap²,

Kiryszewska-Jesionek³

et al. 2023

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Atypical community-acquired pneumonia (CAP) is a lung infection caused by atypical bacteria. It is associated with nonspecific symptoms, the course of the disease is unusual and it poses a serious threat to patients. Even though CAP is quite prevalent, most cases remain undiagnosed, and clinicians rely solely on empirical therapy. The aim of this article is to characterize the most frequently used methods in diagnostics of atypical CAPs and evaluate their efficacy. A literature review showed that most of these techniques are still under development and there is a need for standardized diagnostic algorithms for atypical infections. Molecular panels and serological assays have been especially emphasized as they allow for rapid identification of etiologic agents and antibiotic resistance. StreszczenieAtypowe zapalenie płuc (AZP) to infekcja spowodowana przez bakterie atypowe. Charakteryzuje się nietypowym przebiegiem, mało specyficznymi objawami, a jej powikłania mogą nieść duże ryzyko dla pacjentów. Mimo że prewalencja tej choroby jest wysoka, duża część przypadków nie zostaje prawidłowo zdiagnozowana i klinicyści opierają się jedynie na terapii empirycznej. W artykule przedstawiono metody powszechnie stosowane w diagnostyce AZP wraz z krótką charakterystyką i porównanie ich skuteczności. Przegląd literatury wykazał, że większość technik wciąż jest w fazie rozwoju i nie posiadamy wystandaryzowanych algorytmów postępowania w przypadku atypowych infekcji. Szczególny nacisk został położony na panele molekularne i serologiczne, które pozwalają na szybką, skuteczną identyfikację czynnika etiologicznego oraz ocenę lekooporności.

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Section: Chlamydia Pneumoniaementioning

confidence: 99%

Diagnostics of atypical pulmonary infections

Adamczyk¹,

Parkolap²,

Kiryszewska-Jesionek³

et al. 2023

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“…C. pneumoniae, a gram-negative bacterium, has been present as an individual species since 1989, is a common respiratory pathogen that causes the chronic and persistent respiratory infections (7,8). C. pneumoniae infection not only lead to worldwide widespread respiratory infections such as pneumonia, pharyngitis, bronchitis, and sinusitis, but Original Article Association between Chlamydia pneumoniae infection and lung cancer: a meta-analysis also associated with asthma, chronic obstructive pulmonary disease, and atherosclerosis (9).…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Association between Chlamydia pneumoniae infection and lung cancer: a meta-analysis

Wang¹,

Zhang²,

Gao³

2019

Transl Cancer Res TCR

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Background: The aim of this study is to explore the correlation between Chlamydia pneumoniae (C. pneumoniae) infection and lung carcinoma.Methods: Databases of PubMed, Embase, Embase, Ovid, Wanfang and China National Knowledge Infrastructure (CNKI) database were investigated for eligible literatures from their establishments to February, 2019. Included studies were selected according to specific eligibility criteria. Statistical analysis was performed by RevMan 5.3 software.Results: Thirteen studies with 2,553 lung carcinoma cases and 2,460 controls were eligible for metaanalysis. The pooled results indicated that the C. pneumoniae infection IgA significantly increased the risk of lung carcinoma (OR =3.19; 95% CI, 1.96-5.19; P<0.00001) by random effect model. And for serum IgG, the pooled OR was 2.02 (95% CI, 1.29-3.16; P<0.00001) by using the random effects model. The results indicated that the IgA positive rate was significantly higher in lung cancer patients than healthy controls.Conclusions: This meta-analysis revealed that C. pneumoniae infection may be a potential risk factor for lung carcinoma. However, due to its significant heterogeneity in the included studies, the consequence should be understood with caution.

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“…Chlamydia pneumoniae (C. pneumoniae), a gram-negative bacterium, has been present as an individual species since 1989, is a common respiratory pathogen that causes the chronic and persistent respiratory infections [7,8]. C. pneumoniae infection not only lead to worldwide widespread respiratory infections such as pneumonia, pharyngitis, bronchitis, and sinusitis, but also associated with asthma, chronic obstructive pulmonary disease, and atherosclerosis [9].…”

Section: Introductionmentioning

confidence: 99%

Association Between Chlamydia pneumoniae infection and Lung Cancer: A Meta-Analysis

Wang

Zhang

Gao

2019

Preprint

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Aims: To explore the correlation between Chlamydia pneumoniae infection and lung carcinoma. Methods: Databases of PubMed, Embase, Embase, Ovid, Wanfang and China National Knowledge Infrastructure (CNKI) database were investigated for eligible literatures from their establishments to February, 2019. Included studies were selected according to specific eligibility criteria. Statistical analysis were performed by RevMan 5.3 software. Results: Thirteen studies with 2553 lung carcinoma cases and 2460 controls were eligible for meta-analysis. The pooled results indicated that the C. pneumoniae infection IgA significant increased the risk of lung carcinoma (OR=3.19; 95% CI=1.96-5.19; p < 0.00001) by random effect model. And for serum IgG, the pooled OR was 2.02 ( 95% CI=1.29-3.16; p < 0.00001) by using the random effects model. The results indicated that the IgA positive rate was significantly higher in lung cancer patients than healthy controls. Conclusions: This meta-analysis revealed that C. pneumoniae infection may be a potential risk factor for lung carcinoma. However, due to its significant heterogeneity in the included studies, the consequence should be understand with caution.

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Chlamydia pneumoniae sero-prevalence in Moroccan patients with cardiovascular diseases

Cited by 5 publications

References 29 publications

Diagnostics of atypical pulmonary infections

Diagnostics of atypical pulmonary infections

Association between Chlamydia pneumoniae infection and lung cancer: a meta-analysis

Association Between Chlamydia pneumoniae infection and Lung Cancer: A Meta-Analysis

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