Constituents of Pterocarpus marsupium

Maurya, Rakesh; Ray, Arnab; Duah, Francis; Slatkin, David J.; Schiff, Paul L.

doi:10.1021/np50031a029

Cited by 54 publications

(30 citation statements)

References 12 publications

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“…A subsequent reduction of NO and significant suppression of pro-inflammatory cytokine TNF-a and IL-6 was recorded. [64] Pterocarpus marsupium Roxb: Pterostilbene was identified as an active principle of P. marsupium (PM) extract with potent anti-inflammatory activity [65] . A decreased PGE2 production indicated specific COX-2 inhibition in LPSstimulated human peripheral blood mononuclear cells with IC 50 of approximately 1.0mM [66] .…”

Section: Synonym -Woodfordia Floribundamentioning

confidence: 99%

Potential anti-inflammatory bioactives from medicinal plants of Western Ghats, India

Sekhar¹,

Ruma²,

Kini³

et al. 2012

Phcog Commn

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Section: Synonym -Woodfordia Floribundamentioning

confidence: 99%

Potential anti-inflammatory bioactives from medicinal plants of Western Ghats, India

Sekhar¹,

Ruma²,

Kini³

et al. 2012

Phcog Commn

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“…Flavonoids found in bark are quercetin (flavonol) or rutin (quercetin glycoside) [112]. Stilbenes are diphenylethylene substances [123] such as pinosylvin present in wood or knots [47], resveratrol present in bark [114] or pterostilbene present in wood [115]. Lignans available in wood are derivatives of phenylpropanoid dimers and include secoisolariciresinol, lariciresinol, pinoresinol and eudesmin [116].…”

Section: Polyphenolsmentioning

confidence: 99%

“…Resveratrol, a trihydroxyl derivative of stilbene, can be released from Black Spruce (Picea mariana) bark upon hot water extraction [114]. Pterostilbene, a dimethylated derivative of resveratrol, can be extracted from Pterocarpus marsupium wood with the use of ethyl acetate [115]. Inhibitory effect of pinosylvin, resveratrol and pterostilbene was tested on Selenastrum capricornutum and cyanobacterium Oscillatoria perornata growth [135].…”

mentioning

confidence: 99%

Effect of Lignocellulose Related Compounds on Microalgae Growth and Product Biosynthesis: A Review

et al. 2014

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Microalgae contain valuable compounds that can be harnessed for industrial applications. Lignocellulose biomass is a plant material containing in abundance organic substances such as carbohydrates, phenolics, organic acids and other secondary compounds. As growth of microalgae on organic substances was confirmed during heterotrophic and mixotrophic cultivation, lignocellulose derived compounds can become a feedstock to cultivate microalgae and produce target compounds. In this review, different treatment methods to hydrolyse lignocellulose into organic substrates are presented first. Secondly, the effect of lignocellulosic hydrolysates, organic substances typically present in lignocellulosic hydrolysates, as well as minor co-products, on growth and accumulation of target compounds in microalgae cultures is described. Finally, the possibilities of using lignocellulose hydrolysates as a common feedstock for microalgae cultures are evaluated.Keywords: lignocellulose; hydrolysis; microalgae; cultivation; extraction; bioproducts OPEN ACCESSEnergies 2014, 7 4447 Microalgae: A Source of Valuable CompoundsMicroalgae include several groups of microorganisms that belong to the Prokaryota or Eukaryota, typically found in fresh water or marine systems in single cell forms or in groups. They are capable of performing photosynthesis, producing approximately half of the atmospheric oxygen while using the greenhouse gas carbon dioxide to grow photoautotrophically [1]. Microalgae contain valuable compounds such as lipids, proteins and pigments (Table 1) which have substantial potential for commercial applications. Microalgae cells accumulate lipids which include triacylglycerides (TAGs), polyunsaturated fatty acids (PUFAs) and sterols [2]. These lipids constitute storage materials or membrane structural components in microalgae and can be used for biofuel, food supplement and pharmaceutical production. Indeed, fossil fuels are nowadays still the main source of carbon based fuels, the exploitation of which causes emission of greenhouse CO 2 . Biodiesel production from oil crops is seen as currently the best alternative, but still presents the main drawback of competing with food production for arable land. Therefore, production of biodiesel from TAGs present in microalgae can become an environmentally friendly alternative as microalgae produce oil and fix CO 2 from atmosphere without the necessity of implementing vast arable areas for cultivation [3]. On the other hand, consumption of PUFAs in the human diet can help prevent the development of cardiovascular and mental diseases [4]. Fish are a rich source of PUFAs, but uncontrolled fishing has led to a substantial decrease in the worldwide fish population [5]. Production of PUFAs from microalgae may overcome this problem. On the other hand, sterols from microalgae are important part of the diet for juvenile scallops or prawns in aquaculture hatcheries [6]. Moreover, the high protein content in microalgae makes them a possible fodder for agricultural livestock [7]. In ad...

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“…The heartwood and other parts of the plant contained pterostilbene, pterocarpol, flavonoids, 1-(2', 6'-dihydroxyphenyl)-β-D-glucopyranoside, lupeol, phytosterols, p-hydroxybenzaldehyde and pterocarposide [9][10][11][12][13][14][15][16].…”

Section: Introductionmentioning

confidence: 99%

Isolation, Characterization and Prediction of Biological Activity of Two New Fatty Esters and a Phenol From the Heartwood of Pterocarpus Marsupium Roxb.

Katiyar

Singh

Ali

2017

Int J Pharm Pharm Sci

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Objective: The current investigation involves the isolation, characterization and prediction of biological activity spectra of the phytoconstituents from the ethanolic extract of the heartwood of Pterocarpus marsupium roxb. (Fabaceae). Methods:The heartwood (3 kg) was extracted in alcohol by cold maceration for 21 d and the compounds were isolated by column chromatography. The compounds thus isolated were characterised and their structures were elucidated by using assorted spectral data analysis, i.e., infrared radiation spectroscopy (IR), proton nuclear magnetic resonance ( 1 HNMR), carbon thirteen nuclear magnetic resonance ( 13 Results: Phytochemical investigation of ethanolic extract of the heartwood of Pterocarpus marsupium led to isolate two fatty esters and a phenolic compound characterised as n-octanyl n-octadeca-9,12-dienoate (n-octanyl linoleiate, 1), n-dodecanyl n-octadeca-9,12-dienoate (n-dodecanyl linoleiate, 2) and 2, 3-dioxymethylene phenol (3). These phytoconstituents are reported for first time in the heartwood of Pterocarpus marsupium Roxb. The in silico profiling of these phytoconstituents exhibited their broad spectra of biological activity. Compounds (1) and (2) showed their maximum activity as All-trans-retinyl-palmitate hydrolase inhibitor, anti eczematic, lipid metabolism regulator, etc. and compound (3) was found to be active as membrane integrity agonist, aspulvinone dimethylallyl transferases inhibitor, carminative, neurotransmitter uptake inhibitor, etc.C NMR) and direct analysis in real time mass spectrometry (DART-MS). PASS (prediction of activity spectra for substances) computer program was used to predict the biological activity spectra of the isolated compounds. Conclusion:These isolated phytoconstituents can be used as the marker compounds to establish the identity, quality and purity of the drug. The results of PASS prediction shall be very useful for establishing these phytoconstituents as active pharmacological moieties.

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Constituents of Pterocarpus marsupium

Cited by 54 publications

References 12 publications

Potential anti-inflammatory bioactives from medicinal plants of Western Ghats, India

Potential anti-inflammatory bioactives from medicinal plants of Western Ghats, India

Effect of Lignocellulose Related Compounds on Microalgae Growth and Product Biosynthesis: A Review

Isolation, Characterization and Prediction of Biological Activity of Two New Fatty Esters and a Phenol From the Heartwood of Pterocarpus Marsupium Roxb.

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