The object of this study is the issue of introducing innovations into the process of preparing students of a higher education institution in the subject “Life Safety”. The authors set a goal to open and characterize the fundamental issues associated with the introduction of innovations in the educational process of a university in a particular subject based on a comprehensive systematic analysis of the process of preparing students in universities, as well as basic regulatory legal documents in the field of education and basic professional educational programs and curricula. Moreover, the authors rely not only on approaches and conclusions based on solidarity, but also alternative theoretical ones. The results obtained during the study made it possible to determine ways to solve the issues associated with the correlation of innovative approaches with the subject “Life Safety”. The novelty of the study and its results are determined by the original approach to identifying the characteristic features of innovations in the educational process and studying the systemic links between innovative forms, methods of the educational process and the content of the subject.