“…Despite successful use of BioFETs in some applications (Bergveld, 1991(Bergveld, , 1996Bergveld et al, 1998;Hahm and Lieber, 2004;Cui et al, 2001;Zheng et al, 2005;Star et al, 2003;Kang et al, 2005;Song and Lu, 2006;Liu et al, 2006;Neuberger et al, 2001;Kang et al, 2007); detection of proteins in physiologic buffers (with Na + concentration of 150 mM) has not been convincingly reported. One report purports to establish AlGaN/GaN BioFET protein sensing in physiologic salt (Kang et al, 2007), but presents insufficient information to substantiate this claim (see below).…”