Effects of ganglionated plexi ablation on ventricular electrophysiological properties in normal hearts and after acute myocardial ischemia

Spinal cord stimulation protects against ventricular arrhythmias by suppressing left stellate ganglion neural activity in an acute myocardial infarction canine model

“…MAP duration was determined at 90% repolarization (MAPD 90 ). 13 Neural recording from LSG Neural activity from the LSG was recorded for 1 minute at 3 time points: baseline, 1 hour after SCS or sham SCS, and 15 minutes after AMI. A tungsten-coated microelectrode was inserted into the fascia of the LSG located above the aortic arch, and a ground lead was connected to the chest wall.…”

Prevention of ventricular arrhythmia complicating acute myocardial infarction by local cardiac denervation

“…Ventricular ERP was defined as the longest S1-S2 interval that failed to capture the ventricles. The ERP dispersion was computed as coefficient of variation (CV, standard deviation/mean) of the ERPs at all six recording sites, and the ERP dispersion was also expressed as CV-ERP [21,22].…”

“…The VFT, the minimum voltage to induce sustained VF, was determined in the dogs without spontaneous VF [21]. VF was induced at the same heart rate (200 beats/min) among animals.…”

Neuromodulation for cardiac arrhythmia

“…Although adding GP ablation to PVI may lower the recurrence rate after ablation, a recent study in dogs suggest that GP ablation increases the risk of ventricular arrhythmia during acute MI [88] . It is noteworthy that a standard PVI transects 3 of the 4 major atrial GP and ligament of Marshall [5] .…”