Effects of High-Dose Daidzein on Laying Performance, Egg Quality and Antioxidation in Laying Hens

Abstract

This trial was conducted to evaluate the effects of high-dose daidzein supplements on laying performance, egg quality and antioxidation in laying hens during the late laying period. Seven hundred sixty eight 55-wk-old Hyline Brown were randomly assigned to four groups with 8 replicates of 24 birds each (192 laying hens per group) and fed diets supplemented with 0 (control), 10 mg/kg, 50 mg/kg and 100 mg/kg daidzein for 8 wk in the diets. Egg production, egg mass, feed conversion and egg yolk malondialdehyde were significantly effected by daidzein supplementation (P＜0.05), while there are significant quadratic correlations between average egg production/egg mass/feed conversion/ egg yolk malondialdehyde and daidzein supplementation (quadratic P＝0.022, 0.003, 0.021 and 0.002; respectively). The optimal daidzein supplementation in the diet of laying hens during the late laying period for maximum egg production, egg mass, feed conversion and egg yolk malondialdehyde were 72 mg/kg, 48.5 mg/kg and 56.34 mg/kg and 51.43 mg/kg. Daidzein supplementation significantly improved three calcium-related egg quality indexes (eggshell thickness, eggshell percentage and eggshell strength; P＜0.05) and egg yolk total superoxide dismutase (P＜0.05), linearly. These findings indicated that the daidzein could be a very effective additive to improve laying performance and eggshell quality in the birds during the late laying period, even though the dose of it was high.

Daidzein Supplementation Enhances Embryos Survival by Improving Hormones, Antioxidant Capacity, and Metabolic Profiles of Amniotic Fluid in Sows

“…For instance, chitosan oligosaccharide was found to improve the antioxidant status and metabolic pro les of amniotic uid, which subsequently improved the foetal survival and growth in a pig model [33]. Daidzein is a class of avonoid compounds with estrogen properties and has been reported to have a potential effect on animal reproductive capacity [34][35][36]. In the present study, DAI supplementation signi cantly increased the number of viable embryos at 35 dg.…”

Effects of Dietary Daidzein Supplementation on Reproductive Performance, Serum Hormones, and Reproductive-Related Genes in Rats

“…Furthermore, multiparous sows have been supplemented with dietary daidzein of 1 mg/kg body weight per day during late gestation, which could affect meat quality and skeletal muscle cellularity of the multiparous sow’s offspring [ 5 ]. Concerning poultry subjects, there have also been studies that have shown that daidzein could be a very effective additive to improve laying performance, eggshell quality and egg yolk total superoxide dismutasein in laying hens during the late laying period [ 6 ]. Another study showed that daidzein supplementation could increase egg weight and fertility, and affect serum progesterone (P4), thyroxine (T4) and growth hormone (GH) concentrations in female geese [ 7 ].…”

Supplementing daidzein in diets improves the reproductive performance, endocrine hormones and antioxidant capacity of multiparous sows

“…The effect of daidzein, a natural isoflavonic phytoestrogen with oestrogenic activity ( Kuiper et al, 1998 ), has been studied in a variety of animal species such as rats, laying hens, female geese and sows, and breeding cows ( Liu et al., 2013 ; Zhang et al., 2018 ; Cai et al, 2013 ; Zhao et al., 2013 ; Gentao et al., 1999 ). In the present study, we found that 200 mg/kg daidzein supplementation increased the total numbers of born and born alive, as well as the total litter weight.…”

“…Although our previous research found a potential negative effect of daidzein supplementation at an extremely high dosage on the body weight gain and splenic morphology of piglets ( Xiao et al., 2015 ), most studies using a low or moderate dosage have shown that daidzein supplementation before parturition significantly increases the litter weight and milk yield in sows ( Gentao et al., 1999 ). In addition, the effects of daidzein on the reproductive performance are closely associated with the animal species, sex, dose, and physiological status ( Zhang et al., 2018 ; Cai et al, 2013 ; Zhao et al., 2013 ).…”