Epidemiologic Features of Hand-Foot-Mouth Disease and Herpangina Caused by Enterovirus 71 in Taiwan, 1998–2005

Chen, Kow-Tong; Chang, Hsien-Chih; Wang, Shan‐Tair; Cheng, Yan Tzong; Yang, Jyh Yuan

doi:10.1542/peds.2006-3331

Cited by 272 publications

(221 citation statements)

References 29 publications

Supporting

Mentioning

191

Contrasting

Unclassified

Order By: Relevance

“…25,26 In contrast, other studies proposed risk factors but did not further analyse them or provide statistical evidence. [22][23][24][27][28][29][30][31][32][33][34][35][36][37]57,58 For example, morning body check and health education were described in detail, but their effectiveness and impact were hardly measured which is inappropriate in the context of outbreak investigations (Table 4). [22][23][24][25][26][27][28][29][30][31][32][33][34][35][36][37] Dates for implementation of control measures and notification of outbreaks were often not reported, meaning that delays between outbreak onset and response could not be estimated in most studies.…”

Section: Limitations Of This Studymentioning

confidence: 99%

See 1 more Smart Citation

Best practices to prevent transmission and control outbreaks of hand, foot, and mouth disease in childcare facilities: a systematic review

et al. 2017

View full text Add to dashboard Cite

Section: Limitations Of This Studymentioning

confidence: 99%

“…3,59 Evidence available from other countries has derived mostly from community surveillance or outbreaks among wider population age-groups, without laboratory confirmation of EV71 as the causative strain, and were therefore excluded from this review. 7,44,58,[60][61][62][63][64][65] Recommendations for future outbreaks…”

Section: Limitations Of This Studymentioning

confidence: 99%

Best practices to prevent transmission and control outbreaks of hand, foot, and mouth disease in childcare facilities: a systematic review

et al. 2017

View full text Add to dashboard Cite

“…Physicians are required to report all cases of mumps to the Taiwan CDC within one week of case ascertainment. [35][36][37] We collected all mumps related data that were reported to the Taiwan CDC from January 2006 to December 2011. The data included the patient's age, gender, area of residence, and onset date for the swelling of parotid or other salivary glands.…”

Section: Surveillance For Mumps Infectionmentioning

confidence: 99%

The association between the incidence of mumps and meteorological parameters in Taiwan

et al. 2015

Human Vaccines & Immunotherapeutics

Self Cite

View full text Add to dashboard Cite

These authors equally contributed to this work. Keywords: infectious disease, meteorological parameters, modeling, mumps, weatherMumps is caused by a paramyxovirus. It is an acute, but mild infectious disease. However, approximately 10% of patients with mumps can develop severe meningoencephalitis, disability, and death. Seasonal patterns in mumps vary across countries, but the reasons for this phenomenon remain unclear. The aim of this study was to assess the role of meteorological factors on mumps infection. We investigated the relationships between weather variability and the incidence of mumps in Taiwan using a Poisson regression analysis and case-crossover methodology. Between 2006 and 2011, 6,612 cases of mumps were reported to the Centers for Disease Control, Taiwan (Taiwan CDC). The incidence of mumps showed a significant seasonality in summertime (for oscillation, P < 0.001). The number of mumps started to increase at temperatures of 20 C (r 2 D 0.73, P < 0.001), and the case count of mumps began to decline when the temperatures were higher than approximately 25 C (r 2 D 0.24, p D 0.04), producing an inverted V-shaped relationship. Similarly, the number of mumps began to increase at a vapor pressure of 5-9 hPa (r 2 D 0.87, P < 0.005) and decreased at a vapor pressure higher than 25-29 hPa (r 2 D 0.21, p D 0.05). The number of mumps cases was positively associated with temperature and vapor pressure in the preceding period of the infection. In conclusion, this study showed that the occurrence of mumps is significantly associated with increasing temperature and vapor pressure in Taiwan. Therefore, these factors could be regarded as warning signals indicating the need to implement preventive measures.

show abstract

“…Viral infections by EV71 and CVA16 result in as well as severe illnesses, such as aseptic meningitis, poliomyelitis-like paralysis, and fatal brainstem encephalitis (7)(8)(9). Numerous large outbreaks of HFMD caused by EV71 and CVA16 have been reported in the Asia-Pacific region since 2000 (10)(11)(12), and HFMD remains a common infectious illness in children in this area. Moreover, EV71 and CVA16 co-infection and the potential for new viral recombinants of EV71 and CVA16 to emerge have been documented (13)(14)(15).…”

Section: Introductionmentioning

confidence: 99%

Phage Display-Derived Cross-Reactive Neutralizing Antibody against Enterovirus 71 and Coxsackievirus A16

et al. 2016

View full text Add to dashboard Cite

SUMMARY: Enterovirus 71 (EV71) and coxsackievirus A16 (CVA16) are members of the Picornaviridae family and are considered the main causative agents of hand, foot and mouth disease (HFMD). In recent decades large HFMD outbreaks caused by EV71 and CVA16 have become significant public health concerns in the Asia-Pacific region. Vaccines and antiviral drugs are unavailable to prevent EV71 and CVA16 infection. In the current study, a chimeric antibody targeting a highly conserved peptide in the EV71 VP4 protein was isolated by using a phage display technique. The antibody showed crossneutralizing capability against EV71 and CVA16 in vitro. The results suggest that this phage displayderived antibody will have great potential as a broad neutralizing antibody against EV71 and CVA16 after affinity maturation and humanization.

show abstract

Epidemiologic Features of Hand-Foot-Mouth Disease and Herpangina Caused by Enterovirus 71 in Taiwan, 1998–2005

Cited by 272 publications

References 29 publications

Best practices to prevent transmission and control outbreaks of hand, foot, and mouth disease in childcare facilities: a systematic review

Best practices to prevent transmission and control outbreaks of hand, foot, and mouth disease in childcare facilities: a systematic review

The association between the incidence of mumps and meteorological parameters in Taiwan

Phage Display-Derived Cross-Reactive Neutralizing Antibody against Enterovirus 71 and Coxsackievirus A16

Contact Info

Product

Resources

About