Drug administration is a form of pharmacist-to-nurse delegation that takes up approximately 40% of a nurse's time, including administration, documentation, administration, and monitoring. The purpose of this study was to examine the experience of caregiver drug administration in patients and their families. The method used is qualitative phenomenology. There are 20 participants, including patients and their families. Participant withdrawal was determined by a targeted sampling method. Data analysis was used in Colaizzi's 7-step approach. The study was done by general hospital Pirngadi Medan, Indonesia, from October to June 2021. Data collection was done through indepth interviews using a question guide. As a result, six themes are clarified, (1) responses of patients and families in administering drugs, (2) the role of nurses in administering drugs to patients and families, (3) communication and information from nurses with patients and families, (4) the application of caring in the care and administration of drugs to patients and families, (5) friendly and courteous service from nurses, (6) and family involvement in patient treatment. Involving the family in administration of medicines to the patient and family, service-friendly and courteous nursing services, and the treatment of the patient were needed to approach.