Evaluation of normal erectile function with color flow Doppler sonography

Abstract

To understandbetter the vascular events that occur during normal erection, we used color flow Doppler sonography to examine the erectile process in seven normal subjects. To examine systolic/diastolic velocities and spectral waveform changes before and dunng erection, we used color flow Doppler sonography because of its ability to visualize small vessels with low flow. Subjects and MethodsSeven normal volunteers (age range, 31 -55 years; mean age 40 years) with no known vascular disease or medical conditions were included in the study. All had a history of having normal sexual intercourse as reported by the subjects and their partners, normal erectile response documented by normal nocturnal penile tumescence (NPT), and normal cavemosometry performed after intracorporal injection of papaverine (Eli Lilly, Indianapolis, IN) and Regitine(phentolamine mesylate; Ciba-Geigy; Summit, NJ). Institutional human subjects' approval and informed consent were obtained for all participants.Color flow imaging and spectral waveform analysis of the penile arteries were performed both before and after intracorporal injection of papaverine and Regitmne. Two 21 -gauge needles were placed into the midshaft of the left corpus cavernosum.One needle was used

Reactive oxygen species and erectile dysfunction: possible role of NADPH oxidase

“…In a series of elegant studies, the unique hemodynamics of erection has been elucidated. [12][13][14][15][16][17][18][19][20] The compliance of the corpora increases and arterial resistance decreases, exposing the sinusoids to systemic blood pressure and leading to engorgement of blood in the corpus cavernosum ( Figure 1). As inflow increases and sinusoidal smooth muscle relaxes, subtunical venules draining the corpus cavernosal tissue become compressed Figure 1 Principal events involved in mediating penile erection.…”

Are normal hemodynamic responses invariably associated with normal penile rigidity and potency?

“…Due to the fact that we used cavernosal arteries, blood¯ow velocity for evaluation penile vascular status with 30 cmas and 5 cmas cut-off values for PSV and EDV, respectively. According to Schwartz et al, 22 during the functional evaluation penile vascular system with CDU, IC pressure changes from 40 to 60 mmHg and the mean systolic velocity is 30 cmas in phase 3. During phase 4 usually reversed end-diastolic blood ow velocities are observed, while the mean systolic blood¯ow velocities remain b35 cmas.…”

“…Owing to the fact that blood¯ow velocities measured in this phase might indicate false positive cavernosal arterial insuf®ciency. 22,23 For this reason, we performed measurements of blood¯ow velocities and penile axial rigidity in different periods of CDU assessment.…”

Fisiologia Da Ereção Peniana: Uma Breve Revisão

“…A variação das velocidades sistólica e diastólica e a consequente modificação do espectro ondulatório permitem a subdivisão da ereção em 5 fases. (CHIOU et al, 1998;CHUNG et al, 1997;GARAFFA et al, 2010;RALPH, 2005;SCHWARTZ et al, 1989).…”

“…(CHIOU et al, 1998;CHUNG et al, 1997;DEAN et al, 2005;GARAFFA et al, 2010;GRATZKE et al, 2010;MELDRUM et al, 2014;RALPH, 2005;SCHWARTZ et al, 1989).…”