Experimental study of needle–tissue interaction forces: Effect of needle geometries, insertion methods and tissue characteristics

Jiang, Shan; Li, Pan; Yan, Yu; Li, Jun; Yang, Zhiyong

doi:10.1016/j.jbiomech.2014.08.007

Cited by 121 publications

(92 citation statements)

References 19 publications

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“…101 Similarly, needles can be designed to minimize insertion force and to customize bevel length for particular tissues. [102][103][104] Needle design can also be customized to control deflection, 105 facilitating better positioning of the needle within the lesion. Biopsy needles can be localized within lesions by ultrasound.…”

Section: Biopsy Needle Design and Gaugementioning

confidence: 99%

Needle Biopsy Adequacy in the Era of Precision Medicine and Value-Based Health Care

Pritzker

Nieminen

2019

Archives of Pathology &Amp; Laboratory Medicine

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Context.— Needle biopsy of diseased tissue is an essential diagnostic tool that is becoming even more important as precision medicine develops. However, the capability of this modality to efficiently provide samples adequate for diagnostic and prognostic analysis remains quite limited relative to current diagnostic needs. For physicians and patients, inadequate biopsy frequently leads to diagnostic delay, procedure duplication, or insufficient information about tumor biology leading to delay in treatment; for health systems, this results in substantial incremental costs and inefficient use of scarce specialized diagnostic resources. Objective.— To review current needle biopsy technology, devices, and practice with a perspective to identify current limitations and opportunities for improvement in the context of advancing precision medicine. Data Sources.— PubMed searches of fine-needle aspiration and core needle biopsy devices and similar technologies were made generally, by tissue site, and by adequacy as well as by health economics of these technologies. Conclusions.— Needle biopsy adequacy can be improved by recognizing the importance of this diagnostic tool by promoting common criteria for needle biopsy adequacy; by optimizing needle biopsy procedural technique, technologies, clinical practice, professional education, and quality assurance; and by bundling biopsy procedure costs with downstream diagnostic modalities to provide better accountability and incentives to improve the diagnostic process.

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Section: Biopsy Needle Design and Gaugementioning

confidence: 99%

Needle Biopsy Adequacy in the Era of Precision Medicine and Value-Based Health Care

Pritzker

Nieminen

2019

Archives of Pathology &Amp; Laboratory Medicine

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“…Figure compares conventional bulk biomedical electronics and flexible/stretchable electronics with injectable biomedical electronics, in terms of their implantation techniques, clinical uses, and postsurgical conditions. Explored strategies for injectable biomedical device developments involve controlling thickness and width for avoiding tissue damage, and stiffness and length for precise targeting 32–38. The applications of injectable biomedical devices broadly range from brain sciences to percutaneous therapies, reading vital clinical signs, and healing diseases without major surgical procedures.…”

Section: Introductionmentioning

confidence: 99%

Injectable Biomedical Devices for Sensing and Stimulating Internal Body Organs

et al. 2020

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The rapid pace of progress in implantable electronics driven by novel technology has created devices with unconventional designs and features to reduce invasiveness and establish new sensing and stimulating techniques. Among the designs, injectable forms of biomedical electronics are explored for accurate and safe targeting of deep‐seated body organs. Here, the classes of biomedical electronics and tools that have high aspect ratio structures designed to be injected or inserted into internal organs for minimally invasive monitoring and therapy are reviewed. Compared with devices in bulky or planar formats, the long shaft‐like forms of implantable devices are easily placed in the organs with minimized outward protrusions via injection or insertion processes. Adding flexibility to the devices also enables effortless insertions through complex biological cavities, such as the cochlea, and enhances chronic reliability by complying with natural body movements, such as the heartbeat. Diverse types of such injectable implants developed for different organs are reviewed and the electronic, optoelectronic, piezoelectric, and microfluidic devices that enable stimulations and measurements of site‐specific regions in the body are discussed. Noninvasive penetration strategies to deliver the miniscule devices are also considered. Finally, the challenges and future directions associated with deep body biomedical electronics are explained.

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“…Several studies have investigated the effect of needle geometry on the penetration force [22][23][24]. In addition, it has been suggested that forces generated during insertion of a suturing needle may result in a loss of chondrocytes near the needle [25].…”

Section: Introductionmentioning

confidence: 99%

Characterisation of the surface structure of 3D printed scaffolds for cell infiltration and surgical suturing

et al. 2016

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A note on versions:The version presented here may differ from the published version or from the version of record. If you wish to cite this item you are advised to consult the publisher's version. Please see the repository url above for details on accessing the published version and note that access may require a subscription.For more information, please contact eprints@nottingham.ac.uk Abstract3D printing is of great interest for tissue engineering scaffolds due to the ability to form complex geometries and control internal structures, including porosity and pore size. The porous structure of scaffolds plays an important role in cell ingrowth and nutrition infusion. Although the internal porosity and pore size of 3D printed scaffolds have been frequently studied, the surface porosity and pore size, which are critical for cell infiltration and mass transport, have not been investigated. The surface geometry can differ considerably from the internal scaffold structure depending on the 3D printing process. It is vital to be able to control the surface geometry of scaffolds as well as the internal structure to fabricate optimal architectures. This work presents a method to control the surface porosity and pore size of 3D printed scaffolds. Six scaffold designs have been printed with surface porosities ranging from 3% -21%. We have characterised the overall scaffold porosity and surface porosity using optical microscopy and microCT. It has been found that surface porosity has a significant impact on cell infiltration and proliferation. In addition, the porosity of the surface has been found to have an effect on mechanical properties and on the forces required to penetrate the scaffold with a surgical suturing needle. To the authors' knowledge, this study is the first to investigate the surface geometry of extrusion-based 3D printed scaffolds and demonstrates the importance of surface geometry in cell infiltration and clinical manipulation.

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Experimental study of needle–tissue interaction forces: Effect of needle geometries, insertion methods and tissue characteristics

Cited by 121 publications

References 19 publications

Needle Biopsy Adequacy in the Era of Precision Medicine and Value-Based Health Care

Needle Biopsy Adequacy in the Era of Precision Medicine and Value-Based Health Care

Injectable Biomedical Devices for Sensing and Stimulating Internal Body Organs

Characterisation of the surface structure of 3D printed scaffolds for cell infiltration and surgical suturing

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