The effectiveness of a seeded cover crop to minimize soil nutrient losses was evaluated in a rainfed vineyard. Two sediment tanks were installed (ST2: drainage area with high ground cover (GC: 82%) and ST3: very high GC (89%)) and samples from 26 time-integrated periods (TIP) were collected over 15 months. The average soil nutrient content was previously estimated in the drainage areas of ST2 (Ntotal: 0.967 mg/g; Pava: 0.411 mg/g; Kava: 1.762 mg/g) and ST3 (Ntotal: 0.711 mg/g; Pava: 0.437 mg/g; Kava: 1.856 mg/g). The sediment nutrient concentrations and the sediment/soil enrichment ratios were comparable between ST2 and ST3, but the total loss of nutrients clearly differed among areas. The loss of nutrients in the area with lower GC (379.7 g N-P-K/ha/yr) was 8.3 times higher than in the area with higher GC (45.8 g N-P-K/ha/yr), and this pattern remained during the months with low, medium and high GC: 91.9, 2.1 and 2.1 g N-P-K/ha/month in ST2 and 6.9, 3.0 and 3.5 g N-P-K/ha/month in ST3. The benefits of greater GC promote the environmental and agronomic sustainability by the functions of the cover crop, favoring healthy soils and a reduction in the investment of the farmers in fertilizers. This is very relevant in a postpandemic world under the threat of the war in Ukraine, the lack of fertilizers and the need for a local production of food.