Islamic boarding school has the potential to develop the Islamic economy through the Islamic boarding school business unit. Optimizing business units can create Islamic boarding school economic independence. Even so, the fact is that there are still many Islamic boarding school that have not utilized their potential. One of the Islamic boarding school that has succeeded in achieving economic independence through business units is the Al-Ittifaq Boarding School in Bandung. The aim of this research is to analyze economic activities and factors that influence the economic independence of the Al-Ittifaq Islamic Boarding School. Using Analytical Network Process (ANP), the factors that influence the economic independence of the Al-Ittifaq Islamic Boarding School are divided into four aspects, namely institutional, production, stakeholder, and market aspects. The results show that market aspect has the biggest impact affecting the economic independence in Al-Ittifaq Islamic Boarding School and the four most influential factors are the kiai leadership and management, production information systems, capital, and market availability.