2010
DOI: 10.1016/j.jep.2010.01.036
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Gastroprotective activity of Cinnamomum tamala leaves on experimental gastric ulcers in rats

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Cited by 43 publications
(20 citation statements)
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“…C. tamala has been used in folk medicine as brain tonic and anthelmintic especially for the treatment of anal and rectal diseases [1]. It is reported that C. tamala leaves have gastro-protective effects in experimental animals, may be because of free radical scavenging properties [7]. The plant has also been reported with high phenolic contents and has concentration-dependent antioxidant activities [8].…”
Section: Introductionmentioning
confidence: 99%
“…C. tamala has been used in folk medicine as brain tonic and anthelmintic especially for the treatment of anal and rectal diseases [1]. It is reported that C. tamala leaves have gastro-protective effects in experimental animals, may be because of free radical scavenging properties [7]. The plant has also been reported with high phenolic contents and has concentration-dependent antioxidant activities [8].…”
Section: Introductionmentioning
confidence: 99%
“…Moreover, they are able to inhibit lipid peroxidation and improve increased capillary permeability (Procházková et al, 2011). Recent studies have also reported on anti-ulcer and gastroprotective properties of plant extracts rich in flavonoids, phenolic acid derivatives, and tannins (Arawwawala et al, 2010;Vasconcelos et al, 2010) that present a high free-radical scavenger potential (Mayer et al, 2009;Eswaran et al, 2010). In the present study, the high polyphenolic content in EEC and EAFC suggests that this group of substances, particularly cathequin and quercitrin, which were isolated and identified in ethanolic extract and fractions, may well be one of the active compounds of Campomanesia lineatifolia leaves.…”
Section: Discussionmentioning
confidence: 99%
“…For example, oral Pithecellobium dulce extract for 30 days raised the pH levels in gastric juice and lowered H + /K + ATPase activity comparable to normal levels (Megala and Geetha, 2012). Oral cinnamomum tamala leaf extract twice daily for 5 days caused a 50% reduction in H + /K + ATPase activity (Eswaran et al, 2010). Moreover, mucus protects gastric wall from damage while pepsin damages gastric wall (Venables, 1986).…”
Section: E Othersmentioning
confidence: 99%