Genetic Potential of Interfacial Guided Osteogenesis in Implant Devices.

Letic-Gavrilovic, Anka; Scandurra, Roberto; Abe, Kimio

doi:10.4012/dmj.19.99

Cited by 33 publications

(20 citation statements)

References 190 publications

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“…8 The former determines the reactivity of the implant surface, whereas the latter is essential for interfacial interaction with local tissue around the implant. The stable oxide layer (TiO 2 matrix) presumably aids in the formation of an osteogenic extracelluar matrix at the implant-bone tissue interface, which is important for osseointegration.…”

Section: Introductionmentioning

confidence: 99%

Surface characteristics and structure of anodic oxide films containing Ca and P on a titanium implant material

Zhu

Ong

Kim

et al. 2002

J. Biomed. Mater. Res.

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An anodic oxide film that formed on titanium with a mixture of beta-glycerophosphate sodium (beta-GP) and calcium acetate was investigated. The anodic oxide had interconnected pores (ca. 1-2 microm in diameter) and intermediate roughness (0.60-1.50 microm). In addition, it contained a mixture of amorphous, anatase, and rutile oxides. With an increase in the anodizing voltage and/or concentration of calcium incorporated into the oxide, the degree of oxide crystallinity increased. However, with an increase in the concentration of beta-GP, the degree of oxide crystallinity decreased. It was concluded that the surface roughness, oxide crystallinity, and surface composition of the anodic oxide were dependent on the voltage, current density, and concentration of the electrolyte. It was also concluded that the anodized surface could be optimized for maximum osseointegration.

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Section: Introductionmentioning

confidence: 99%

Surface characteristics and structure of anodic oxide films containing Ca and P on a titanium implant material

Zhu

Ong

Kim

et al. 2002

J. Biomed. Mater. Res.

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“…The biological response to titanium depends on the surface chemical composition and the ability of titanium oxides to absorb molecules and incorporate elements [92]. Surface topography plays a fundamental role in regulating cell behaviour, e.g.…”

Section: Plasma Electrolytic Oxidation Treatmentmentioning

confidence: 99%

Titanium and Titanium Alloys as Biomaterials

Viteri¹,

Fuentes²

2013

Tribology - Fundamentals and Advancements

103

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“…Titanium (Ti) is the standard material used for dental and orthopedic implants, thanks to its very good strength, corrosion resistance and biocompatibility [1–2]. Despite the very high success rate of Ti dental implants (>90%), there is still room for optimization of osteointegration, particularly for diabetics, smokers and oncology patients [3].…”

Section: Introductionmentioning

confidence: 99%

Electrochemical coating of dental implants with anodic porous titania for enhanced osteointegration

Shayganpour

Rebaudi²,

Cortella³

et al. 2015

Beilstein J. Nanotechnol.

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SummaryClinical long-term osteointegration of titanium-based biomedical devices is the main goal for both dental and orthopedical implants. Both the surface morphology and the possible functionalization of the implant surface are important points. In the last decade, following the success of nanostructured anodic porous alumina, anodic porous titania has also attracted the interest of academic researchers. This material, investigated mainly for its photocatalytic properties and for applications in solar cells, is usually obtained from the anodization of ultrapure titanium. We anodized dental implants made of commercial grade titanium under different experimental conditions and characterized the resulting surface morphology with scanning electron microscopy equipped with an energy dispersive spectrometer. The appearance of nanopores on these implants confirm that anodic porous titania can be obtained not only on ultrapure and flat titanium but also as a conformal coating on curved surfaces of real objects made of industrial titanium alloys. Raman spectroscopy showed that the titania phase obtained is anatase. Furthermore, it was demonstrated that by carrying out the anodization in the presence of electrolyte additives such as magnesium, these can be incorporated into the porous coating. The proposed method for the surface nanostructuring of biomedical implants should allow for integration of conventional microscale treatments such as sandblasting with additive nanoscale patterning. Additional advantages are provided by this material when considering the possible loading of bioactive drugs in the porous cavities.

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Genetic Potential of Interfacial Guided Osteogenesis in Implant Devices.

Cited by 33 publications

References 190 publications

Surface characteristics and structure of anodic oxide films containing Ca and P on a titanium implant material

Surface characteristics and structure of anodic oxide films containing Ca and P on a titanium implant material

Titanium and Titanium Alloys as Biomaterials

Electrochemical coating of dental implants with anodic porous titania for enhanced osteointegration

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