Histamine Levels in Human Skin

Johnson, Herbert H.

doi:10.1001/archderm.1957.01550240044008

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Relationship Between the Severity And The Course1

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1960

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Cited by 20 publications

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“…Table II shows a connection between the severity of the clinical symptoms and the increase of plasma histamine levels after injection of propanidid. Apparently, the first noticeable symptoms of histamine release in man are development of tachycardia and erythema, especially in the skin of the face in which the highest histamine content is found of all human skin (Johnson, 1957;Zachariae, 1964; for survey see Lorenz and Werle, 1971). Then follow bronchospasm, oedema formation and hypotension, the severity of which correlates largely with the increase of plasma histamine concentration.…”

Section: Relationship Between the Severity And The Coursementioning

confidence: 99%