Kondensierte Isochinoline, VII. Synthesen und Reaktionen der s ‐Triazolo[5.1‐ a ]isochinoline

Abstract

(14) is heated with alkali competition is observed between the isomcrization to 12d and a ring cleavage to I-aminoisoquinoline. The proton in 5-position of 12d can be exchanged by deuterium in basic medium and with butyl lithium a Li-salt is formed which is stable at -70" and decomposes a t 20" to form 13. At -70" 12d undergoes typical metal organic reactions (to 16a-c). The compouilds 12 are hydrogenated or oxidized selectively in 5.6-position (to 18 and 19, resp.). Mit

Isomerization by ligand shuffling along a Cr24+unit: further reactions leading to cleavage of a quadruple bond

“…Anhydrous CrCl 2 was purchased from Strem Chemicals, Inc. N,NЈ-di(2-pyridyl)formamidine (HDpyF) was prepared according to a published procedure. 8 referenced to CD 2 Cl 2 (δ 5.32 ppm). The electronic absorption spectra were measured on a Shimadzu UV-2501PC spectrophotometer.…”

Dinuclear and Heteropolynuclear Complexes Containing Mo24+Units

“…Solvents were purified by conventional methods and were freshly distilled under nitrogen prior to use. HDpyF was prepared by high-temperature (175 °C) condensation of 2-aminopyridine with triethyl orthoformate, and Mo 2 (OOCCF 3 ) 4 was prepared according to a published procedure . Anhydrous CoCl 2 and CrCl 2 were purchased from Aldrich and used without further purification.…”

A convenient synthesis of 2-substituted [1,2,4]triazolo-[1,5-a]quinolines and [1,2,4]triazolo[5,1-a]isoquinolines

“…1-a]isoquinoline (13a). 27,28 Procedure B. Colorless crystals, 0.52 g (57%); mp 84 °C (n-hexane; lit. 27 23 (0.80 g, 5 mmol; instead of the tosylate 8) and water (11 mL; instead of an aqueous potassium hydroxide solution) after 6 h afforded 13c (0.98 g, 80%).…”

“…27,28 Procedure B. Colorless crystals, 0.52 g (57%); mp 84 °C (n-hexane; lit. 27 23 (0.80 g, 5 mmol; instead of the tosylate 8) and water (11 mL; instead of an aqueous potassium hydroxide solution) after 6 h afforded 13c (0.98 g, 80%). When this reaction was carried out under exclusion of air in a closed reaction flask no product precipitated after 6 h. After opening the flask and continued stirring 13c precipitated within 2 h and was isolated by filtration (0.97 g, 79%).…”