Parameters of Embryogenesis in Zebrafish Danio rerio as Indicators of the Ecological Toxicity of Zinc Oxide Nanoparticles

Toxicity of boron and vanadium nanoparticles on Danio rerio embryos – Phenotypical, biochemical, and behavioral alterations

“…In the present study, in addition to inducing malformations, 10 mg/L VNPs also delayed hatching of embryos. Other authors also reported impaired hatching at ≥0.5 mg/L of CuO (≤50 nm) (Aksakal and Ciltas, 2019), ≥0.1 mg/L ZnO (10-12 nm) (Morgalev et al, 2018), and ≥1 mg/L of ZrO (15-20 nm) NPs (Karthiga et al, 2019). Delaying hatching may be due to blockage of the secretory function of hatching gland cells, inactivation of chorionase (hatching enzyme), suppression of embryogenesis, and an impaired ability of the larvae to break the chorion due to the presence of malformations (Aksakal and Ciltas, 2019;Morgalev et al, 2018).…”

Green Synthesis of Copper Oxide Nanoparticles from Magnolia Champaca Floral Extract and its Antioxidant & Toxicity Assay using Danio Rerio

“…Researchers believe the zebrafish is an ideal model for in vivo advancement of new drugs. Most researchers use zebrafish embryos simply because of their rapid growth, transparency and their small size [16]. Their fast-growing tissues provide an opportunity to predict the reaction properties of new drugs [17].…”