Pharmacognostical and Phytochemical Evaluation Leaves Extract of Garcinia daedalanthera Pierre

Abstract

Background: Garcinia daedalanthera is an Indonesian plant where commonly found in Sulawesi, Indonesia and spread out in the forest. Garcinia daedalanthera is one of Clusiaceae family that have been scientifically proven to provideantidiabetic and antioxidant activity but never been examined in pharmacognosy parameters. Pharmacognostical parameters of the leaves were studied with the aim of drawing the pharmacopoeial standards for this species. Methods: The present study was aimed to analysis the pharmacognosy of Garcinia daedalanthera including leaf morphology, microscopic characteristics, physicochemical parameters, phytochemical study, contaminant analysis and FTIR spectrum analysis. Results: The phytochemical analysis revealed the presence of flavonoids, saponins, tannin, steroids and phenols.The moisture content was 2.35%, total ash 2.51%, acid insoluble ash 0.05%, total flavonoid and phenolic content were found to be 3.121% and 14.36% (w/w). The level of Arsenic (As), Cadmium (Cd) and lead (Pb) were found under the limit (0.357 ppm) and the extract of

Cholesterol-lowering Effects of Extract from Garcinia daedalanthera in Hyperlipidemic rats

“…Garcinia daedalanthera has high level of polyphenols. 6 Polyphenols such as flavonoids, which possess antioxidative activity that suggested to have a preventive effect for arteriosclerosis (Mojzisova and Kuchta, 2001). The extract of this plant was standardized according to Farmakope Herbal Indonesia in order to get reproducible product and to provide the predictable efficacy.…”

“…10 Garcinia daedalanthera contains high level of phenolic and flavonoids compounds. 6,7 This study was aim to study antihyperlipidemic activity of ethanolic extracts of Garcinia daedalanthera, in vivo.…”

“…Garcinia daedalanthera contains high level of phenolic and flavonoids compounds. 6 The therapeutic properties of Garcinia daedalanthera have studied recently. 7 This study was aim…”