“…Sub-micron diamonds allow the outstanding material characteristics of diamond relating to its electrical, thermal, chemical, and mechanical properties to be applied on microscopic scales. Some pertinent examples of this include transistors with excellent heat spreading, − chemically inert particles for drug delivery, − and mechanically stable micro-electro-mechanical system structures for nanoscale sensing applications. , However, as diamond gets smaller, the surface area increases, and so does the volume of any non-diamond surface content, hydrogen terminations, and disordered, sp 2 , and non-diamond carbons in the well-known core–shell model. − Non-diamond functional group terminations are preferred for conjugating certain types of proteins, however, reconstructed sp 2 carbon terminations are considered a hindrance as this causes particle agglomeration; ,, hence, there has been much research into rigorous purification methods. − Hence, characterization of non-diamond impurities on nano-diamond is a prominent research area for assessing its quality in various applications.…”