Possibilities of bioimpedance analysis in the diagnosis of obesity

Abstract

The use of additional parameters obtained with the help of bioimpedance analysis allows correctly to establish or exclude the diagnosis of obesity when conducting a survey of men. We proposed the «fat mass index» index, which has the greatest sensitivity and specificity in the diagnosis of obesity. The use of ROC-analysis allowed setting threshold values (cut-off points) in samples of a number of bioimpedanceometry indicators for diagnosing obesity according to known grades of body mass index according to the classification of the World Health Organization. Thus, for the visceral fat area, this boundary corresponds to 103,95 cm2, the fat mass index is 7,33 kg / m2, the fat mass is 22,45 kg, the percentage of body fat is 24,55% and the degree of abdominal obesity is0, 94%. Exceeding the above thresholds can be used as additional criteria for diagnosing obesity. The existence of phenotypic and metabolic heterogeneity of persons with normal body weight and obese patients is shown. It was confirmed that 93,3% of patients are metabolically unwell, and 6,7% are metabolically healthy. A similar pattern is also observed with normal body weight: a larger pool (92,4%) is metabolically healthy, and a small proportion of people (7,6%) are metabolically unwell. At present, normative values do not exist for all parameters obtained with the help of bioimpedance analysis; therefore, in the complex survey of men, the use of the optimal cut-off threshold for the studied indicators will help to identify individuals with true obesity. The results obtained should increase the diagnostic value of biomedance analysis of body composition and help to conduct an effective evaluation of curative and preventive measures for obesity by comparing the considered indicators in dynamics.