2015
DOI: 10.1080/03602559.2014.935425
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Rutin-Chitosan Nanoparticles: Fabrication, Characterization and Application in Dental Disorders

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Cited by 39 publications
(25 citation statements)
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“…Still, the peak of endothermic melting for KAE-LC NPs was not observed due to the shifted peak of KAE ( Figure 5(B)). Also, the peak of the chitosan (Patila and Jobanputraa 2015) shifted from 190 to 150 C and the peak of the KAE diminished. It can be assumed, through the proof of inclusion, that the presence of KAE in the lecithin/chitosan nanoparticles caused the melting point disappear due to its thermal profile.…”
Section: Intermolecular Interactions Between Kae and Kae-lc Npsmentioning
confidence: 94%
“…Still, the peak of endothermic melting for KAE-LC NPs was not observed due to the shifted peak of KAE ( Figure 5(B)). Also, the peak of the chitosan (Patila and Jobanputraa 2015) shifted from 190 to 150 C and the peak of the KAE diminished. It can be assumed, through the proof of inclusion, that the presence of KAE in the lecithin/chitosan nanoparticles caused the melting point disappear due to its thermal profile.…”
Section: Intermolecular Interactions Between Kae and Kae-lc Npsmentioning
confidence: 94%
“…In the rutin CST TP-loaded FTIR spectrum, the success of rutin encapsulation is indicated by the presence of rutin characteristics in the encapsulation product. The emergence of new absorption bands such as 1604.77 cm -1 , 1458.18 cm -1 shows the aromatic C=C vibration of rutin flavonoids (Natalia dkk., 2017), absorption 1296,16 cm -1 indicates CO from the phenolic group and 1651.07 cm -1 indicate C=O uptake in rutin flavononoid (Patil and Jobanputra, 2015). The presence of absorbent bands in typical aromatic rings and other rutin absorption bands originally absent in the FTIR spectrum of chitosan and CS-TPP matrix indicates the presence of rutin compounds contained in CS-TPP microparticles.…”
Section: Fourier Transform Infrared (Ftir)mentioning
confidence: 99%
“…In this research, Fourier Transform Infrared (FTIR) analyzes of rutin, chitosan, chitosan-TPP, and rutin contained in chitosan-TPP ( Figure 6). In rutin FTIR spectra, the absorption bands at wave numbers 1651.07 cm -1 and 3410.15 cm -1 indicates C=O uptake in rutin flavononoid and vibration of O-H stretching (Patil and Jobanputra, 2015). Vibration C=C which is characterization of aromatic group of flavonoids is shown in absorption bands 1604.77 cm -1 and 1458.18 cm -1 (Natalia et al, 2017).…”
Section: Fourier Transform Infrared (Ftir)mentioning
confidence: 99%
“…33 Moreover, PF-127 has been reported to be the least toxic of commercially available copolymers. 34 Based on the above mentioned facts, and in continuation with our research on nanoparticles in dental disorders, 17 in the proposed study, we aim to investigate the use thermoresponsive triggered in situ gelling system (CGNPs-gel) as a vehicle for delivery of gallic acid in treatment of dental diseases, which may overcome the problems of conventional dosage form, besides providing sustained release by using a combination of pluronic F127 biodegradable polymer. The study also focused on the antimicrobial activity of CGNPs-gel against isolated pathogens, i.e., Bacillus species and Bacillus pumilus and Pseudomonas aeurogenosa, Acinetobacter junii, Enterococcus faecalis from dental caries and abscess respectively.…”
Section: Introductionmentioning
confidence: 98%
“…Literature revealed that drug encapsulated in nanoparticles matrix is more stable in simulated salivary fluid (SSF) than bare drug. 17 Therefore, in the present study, we intend to prepare in situ gel containing gallic acid-loaded chitosan nanoparticles (CGNPs) for the treatment of periodontal disease.…”
Section: Introductionmentioning
confidence: 99%