Studies on the Ultraviolet Absorption Spectra of Coumarins and Chromones.<sup>1</sup> Part I

Ganguly, Banti; Bagchi, P.

doi:10.1021/jo01118a023

Cited by 60 publications

(12 citation statements)

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“…energy level). However, it has been shown that a methyl group substituting different positions (a methyl group present either in the benzene or in the pyrone ring) in coumarin and chromone fails to cause any significant bathochromic shift of the main absorption bands [67] . This was considered to be due to the weak auxochromic property of the methyl group.…”

Section: Discussionmentioning

confidence: 99%

Development of a Novel Fluorophore for Real-Time Biomonitoring System

et al. 2012

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Rapid in-field diagnosis is very important to prevent the outbreak of various infectious and contagious diseases. Highly sensitive and quantitative detection of diseases can be performed using fluorescent immunochemical assay with specific antigen-antibody binding and a good quality fluorophore. This can lead to the development of a small, portable, quantitative biosensor to transmit diagnostic results to a control center in order to systematically prevent disease outbreaks. In this study, we developed a novel fluorophore, coumarin-derived dendrimer, with high emission intensity, strong signal brightness, and high photostability. It is easily coupled with biomolecules and emits strong and stable fluorescence at 590 nm with excitation at 455 nm. Application to fluorescent immunochromatographic test (FICT) showed that the novel coumarin-derived dendrimer bioconjugate could detect antigens at amount as low as 0.1 ng. The clinical results and the spectral characteristics of the novel coumarin-derived dendrimer open, for the first time, the possibility of developing a cost/energy efficient LED-based portable quantitative biosensor for point-of-care (POC) disease diagnosis, which can permit real time monitoring (U-healthcare system) by a disease control center.

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Section: Discussionmentioning

confidence: 99%

Development of a Novel Fluorophore for Real-Time Biomonitoring System

et al. 2012

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“…The UV absorptions at 231, 246, 254 sh, and 298 nm and IR absorptions at 1632 cm −1 (a conjugated carbonyl group), 1604 and 1579 cm −1 (an aromatic ring) accompanying the 13 C NMR resonnance at δ 178.4 (C-4), suggested a chromone skeleton [12]. The 1 H NMR spectrum showed two aromatic protons with ortho -coupling at δ 6.92 (1H, d, J = 8.8 Hz, H-6) and 8.03 (1H, d, J = 8.8 Hz, H-5), which was assignable due to being next to the carbonyl group of chromone moiety.…”

Section: Resultsmentioning

confidence: 99%

“…solution gave a bathochromic shift. The IR absorption at 3194 cm −1 (a hydroxy group), 1626 cm −1 (a conjugated carbonyl group), 1584 and 1482 cm −1 (an aromatic ring) suggested the presence of a phenolic chromone skeleton [12], which was also supported by a 13 C NMR resonance of C-4 (δ C 178.3) and δ H 7.35 (1H, br s, OH-6) in 1 H NMR spectrum. The 1 H NMR data was similar to that of 5 except two meta -coupled protons of H-5 (δ 6.90) and H-7 (δ 7.96), one hydroxy group in C-6 of 2 replaced two ortho -coupled protons of H-5 and H-6, and one hydroxy group (δ 8.91, br s) in 5 .…”

Section: Resultsmentioning

confidence: 99%

Secondary Metabolites of the Endophytic Fungus Lachnum abnorme from Ardisia cornudentata

Chang

Lin

Chen

et al. 2016

IJMS

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Abstract:Fractionation of an EtOAc-soluble fraction of the solid fermentate of an endophytic fungus, Lachnum abnorme Mont. BCRC 09F0006, derived from the endemic plant, Ardisia cornudentata Mez. (Myrsinaceae), resulted in the isolation of three new chromones, lachnochromonins D-F (1-3), one novel compound, lachabnormic acid (4), along with nine known compounds (5-13). Their structures were elucidated by spectroscopic analyses. Alternariol-3,9-dimethyl ether (6) was given the correct data as well as 2D spectral analyses for the first time. This is the first report of the isolation of one unprecedented compound 4 from Lachnum genus, while all known compounds were also found for the first time from Lachnum. The effects of some isolates (3, 4, 7-9, 10, and 13) on the inhibition of nitric oxide (NO) production in lipopolysaccharide (LPS)-activated RAW 264.7 murine macrophages were also evaluated. Several compounds exhibited weak inhibitory activity on lipopolysaccharide (LPS)-stimulated NO production in RAW 264.7 macrophages.

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“…Which is compatible with this complex having square planer geometry [24] .This is supported by Magnetic moment value of complex. The electronic spectra of ligand was shown the 381nm-284 nm indicate n-π* and π-π* transition [25][26].…”

Section: Electronic Spectramentioning

confidence: 99%

Synthesis, Characterization and Biological Screening of Cu (II)-3-Formylchromone Derivative Complex

Kolhe¹,

Jadhav²,

Takate³

et al. 2014

IOSRJAC

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The complex of 3-formyl chromone derivative ligand with the Cu(II) complex was isolated in the solid form. Which have been characterized using FTIR spectrums. The FTIR spectrum shows bands for characteristic frequencies at 1604 cm-1 indicates C=O group, belongs to pyrone ring. The frequency at 510 to 596 cm-1 and band at 916 to 964 cm-1 indicates the M-O and M-O=C-in pyrone ring respectively. The UV-Vis spectroscopy shows that carbonyl of aldehyde group and carbonyl of pyrone ring of chromone of ligand shows n-π*and π-π* transition and complex shows electronic absorption at 369nm due to the 2 B 1 g → 2 B 2 g transition. Thermo Gravimetric Analysis (TGA) of complexes and ligand was carried out to determine the procedural and decomposition temperatures. The temperature range in which decomposition occurs in the range between 209°C to 350°C. The magnetic properties were determined from Gouy balance method. The number of unpaired electron found in complex of Cu(II)-3-formylchromone derivative was one and it has dsp2 hybridization. The complex is soluble in DMSO. The molar conductance of the complex are measured in DMSO at a concentration 10-3 M.The ligand and their copper complexes were screened for antimicrobial activities by the agar well diffusion technique using DMSO as solvent. The complexes were checked for their biological activity by using, Escherichia coli, and Bacillus subtilis bacteria.

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Studies on the Ultraviolet Absorption Spectra of Coumarins and Chromones.¹ Part I

Cited by 60 publications

References 0 publications

Development of a Novel Fluorophore for Real-Time Biomonitoring System

Development of a Novel Fluorophore for Real-Time Biomonitoring System

Secondary Metabolites of the Endophytic Fungus Lachnum abnorme from Ardisia cornudentata

Synthesis, Characterization and Biological Screening of Cu (II)-3-Formylchromone Derivative Complex

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Studies on the Ultraviolet Absorption Spectra of Coumarins and Chromones.1 Part I

Cited by 60 publications

References 0 publications

Development of a Novel Fluorophore for Real-Time Biomonitoring System

Development of a Novel Fluorophore for Real-Time Biomonitoring System

Secondary Metabolites of the Endophytic Fungus Lachnum abnorme from Ardisia cornudentata

Synthesis, Characterization and Biological Screening of Cu (II)-3-Formylchromone Derivative Complex

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Studies on the Ultraviolet Absorption Spectra of Coumarins and Chromones.¹ Part I