Bisphenol A (BPA) is an environmental defilement released mainly from polycarbonate plastic and epoxy resins. The main toxicological impact of BPA is its endocrine disruptor activities. Its structural features confer the ability to bind to both estrogen receptor (ER) subtypes. Furthermore, we recently reported that BPA aggravates male reproductive hormones. In addition to its endocrine disruptor properties, we have also reported that BPA possesses oxidant activity which is able to trigger oxidative stress. Several types of research previously reported that oxidative stress may cause hormonal imbalance and vice versa. However, the relation of both the toxicological properties of BPA is poorly understood. In this study, we found that oral testosterone undecanoate treatment in BPA-induced rats does not prevent decreasing serum superoxide dismutase, glutathione peroxidase, and catalase, and increasing serum malondialdehyde. Oral N-acetyl cysteine (NAC) in BPA-induced rats also does not attenuate decreasing total testosterone levels. These results suggest that the oxidant effect and endocrine disruptor property of BPA can be separated and might not interfere with one another. Therefore, future treatment in any pathological condition resulting from BPA exposure has to be carried out with more comprehensive approaches rather than focusing on its endocrine disruptor activity.

Bakteri Asam Laktat (BAL) memiliki kemampuan dalam menghambat pertumbuhan bakteri patogen, salah satunya adalah BAL isolat 18A. Penelitian ini bertujuan untuk  menentukan spesies BAL dari isolat 18A dengan uji konvensional dan uji KIT API 50 CH. Penelitian ini merupakan penelitian observasional deskriptif, dengan objek penelitian berupa bakteri asam laktat isolat 18A asal kolon sapi bali. BAL isolat 18A direkulturisasi, dengan penumbuhan pada media MRS, uji katalase, dan  pewarnaan Gram. Uji identifikasi isolat dengan uji produksi gas CO2, uji pertumbuhan pada NaCL 15%, uji pertumbuhan pada Suhu 100C, dan uji pertumbuhan pada pH 9,6. Konfirmasi isolat juga dilakukan dengan uji kit API (Standard Analytical Profile Index) 50 CH. Hasil rekulturisasi menunjukkan isolate 18A mampu tumbuh dengan baik pada media MRS broth, bersifat katalase negatif, Gram positif, berbentuk bulat, dan berantai. Hasil identifikasi mengindikasikan bahwa isolat 18A bersifat homofermentatif, mampu tumbuh pada suhu 100C, dan tidak tumbuh pada pH 9,6. Uji  fermentasi dengan menggunakan perangkat kit API 50 CH, menunjukkan bahwa isolat 18A mampu mendegradasi  15 komponen gula, yaitu komponen gula no : 5, 10, 11, 12, 13, 22, 24, 25, 26, 27, 28, 29, 30, 31, dan 39. Hasil identifikasi secara konvensional dapat disimpulkan bahwa isolate 18A merupakan genus Lactococcus. Dan berdasarkan uji konfirmasi menggunakan Kit API 50 CHL disimpulkan bahwa isolat 18A merupakan bakteri Lactococcus Lactis ssp lactis 1.

Lumpy skin disease (LSD) is one of the diseases that pose a threat to the livestock industry because it can cause large economic losses. The disease was first discovered in the country of Zambia in 1929. In Indonesia, LSD was first discovered in early 2022 in Indragiri Hulu Regency, Riau. This disease is caused by a virus belonging to the genus Capripoxvirus, subfamily chordopoxvirinae, family Poxviridae. The LSD virus has a limited host and does not infect non-ruminant hosts. A characteristic clinical symptom of LSD is the appearance of nodules on the skin. Diagnosis of this disease can be done by looking at typical clinical symptoms, laboratory tests such as virus isolation, serological tests (serum neutralization test, virus neutralization test (VNT), agar gel immune diffusion, indirect ELISA, and indirect fluorescent antibody technique (IFAT)), real time and conventional PCR, immunohistochemistry, LAMP, and IPMA. Prevention and control of LSD disease can be done in several ways such as vaccination, vector control, restriction of livestock traffic, strict quarantine and stamping out.

Penyakit masih menjadi kendala utama peternak di Indonesia, terutama peternakan rakyat, hal ini dikarenakan kondisi iklim tropis dan sumber daya peternak yang tergolong rendah pengetahuannya tentang penyakit, sehingga kurang memperhatikan dalam memelihara ternaknya, terutama yang berkaitan pencegahan dan pengendalian penyakit. Desa Salarri merupakan salah satu desa yang terdapat di Kecamatan Limboro, Polewali Mandar. Sebagian besar masyarakat di desa tersebut berprofesi sebagai peternak sapi dan kambing. Berdasarkan hasil identifikasi permasalahan bersama dengan Kepala Desa setempat diperoleh bahwa minimnya pengetahuan para peternak di Desa Salarri terkait dengan penyakit pada sapi dan kambing serta upaya pencegahannya. Sehingga perlu dilakukan sosialisasi mengenai penyakit pada sapi dan kambing serta pencegahannya di Desa Salarri Kecamatan Limboro, Polewali Mandar. Kegiatan ini dilaksanakan pada hari Kamis, 24 Maret 2022 di Aula Kantor Desa Salarri. Adapun metode yang digunakan pada kegiatan ini adalah ceramah dan tanya jawab. Sasaran dari kegiatan ini adalah peternak yang ada di Desa Salarri. Hasil yang diperoleh dari kegiatan ini adalah terlaksananya kegiatan sosialisasi dengan baik dan lancar. Dengan adanya kegiatan ini para peternak di desa tersebut mendapatkan pengetahuan baru mengenai penyakit pada sapi dan kambing serta upaya pencegahannya.The disease is still the main obstacle for breeders in Indonesia, especially on smallholder farms, this is due to tropical climate conditions and breeders' resources which are relatively low in knowledge about diseases, so they pay less attention to raising livestock, especially those related to disease prevention and control. Salarri Village is one of the villages located in Limboro District, Polewali Mandar. Most of the people in the village work as cattle and goat breeders. Based on the results of the identification of problems with the local Village Head, it was found that the farmers in Salarri Village lacked knowledge regarding diseases in cattle and goats and their prevention efforts. So it is necessary to disseminate information about diseases in cattle and goats and their prevention in Salarri Village, Limboro District, Polewali Mandar. This activity was held on Thursday, March 24, 2022, in the Salarri Village Office Hall. The method used in this activity is lecture and question and answer. The target of this activity is farmers in Salarri Village. The results obtained from this activity are the implementation of socialization activities well and smoothly. With this activity, farmers in the village gain new knowledge about diseases in cattle and goats and their prevention efforts.

The purpose of this study was to prove that the administration of Jati (Guazuma ulmifolia Lamk) leaves extract improves the lipid profile of dyslipidemic male Wistar rats. Subjects were 20 rats (Rattus norvegicus), male, Wistar strain, dyslipidemia (total cholesterol ≥ 200 mg dl-1), aged 2 months old, weighing 180-200 grams. The control group (10 rats) were given a placebo of 3 ml aquadest (P0) and the treatment group was given extracts of the Jati (Guazuma ulmifolia Lamk) leaves extract of 25 mg kg-1 BW (P1). Before and after treatment for 14 days, total cholesterol, triglyceride, LDL, and HDL levels were examined. The results showed that in the P0 group there were no changes in total cholesterol, triglyceride, LDL, and HDL levels (p>0.05), whereas the P1 group experienced a decrease in total cholesterol, triglyceride and LDL levels (p<0.05) and an increase in HDL levels (p<0.05). The results of this study indicated that the Jati leaves extract was effective to improve the lipid profile of dyslipidemic rats. It was necessary to compare the effectiveness of Jati leaves extract with synthetic dyslipidemia drugs used in the community such as statin.