The present study evaluates the effect of flaxseed oil (FXO) supplementation on adipose tissue macrophages (ATM’s), E and D series resolvin (Rv) levels and adipose tissue inflammation. Male C57BL/6J mice were divided into five groups (n = 5): lean group (given standard chow diet), HFD group given high fat diet (approx. 18 weeks) till they developed insulin resistance and 4, 8 or 16 mg/kg group (HFD group later orally supplemented with 4, 8 or 16 mg/kg body weight flaxseed oil) for 4 weeks.The present study showed that FXO supplementation led to enhanced DHA, EPA, RvE1-E2, RvD2, RvD5- D6, IL-4, IL-10 and arginase 1 levels in ATMs together with altered immune cell infiltration and reduced NF-κB expression. The FXO supplementation suppresses immune cell infiltration into adipose tissue and alters adipose tissue macrophage phenotype towards the anti-inflammatory state via enhancement of E and D series resolvins, arginase 1 expression and anti-inflammatory cytokines level (IL-4 and IL-10.) leading to amelioration of insulin resistance in flaxseed oil supplemented HFD mice.

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In Ayurveda Tundikari is described under Mukharoga, which is characterized by Jwara (fever), Pradaha (burning sensation), Vedana (pain), Sotha (swelling), Galadhakaranapida (pain during deglutition). Tundikari may be correlated with tonsillitis. Inflammation of the tonsil is known as tonsillitis. Tonsillitis most commonly occurs in pediatric age groups. The incidence of this disease is about 7% of all visits to pediatrician. In the present study a 15 years old male patient suffering from tundikari (acute tonsillitis), since last 3 days. He was treated with Ayurvedic Shaman aushadi (kanchanar Guggulu, Laxmivilas Rasa, Khadira Vati) which gives an effective result.

Ankylosing spondylitis is a most troublesome health hazards all over globe the patient of this gradually become physically challenged and mentally depressed. There are no such safe and effective remedy in modern medicine whereas Ayurvedic treatment has showed an excellent curative effect in a case of Ankylosing spondylitis with HLA-B27 positive. As Ayurveda usually delt with most of the neuro-musculo-skeletal disorder in a significant success manner through the conceptual remedies of Vata Vyadhi. In present study a 28-year-old young boy become bedridden by the ailment Ankylosing spondylitis with the evidence of HLA-B27 positive, some Panchakarma therapy along with Snehana and Swedana and internal Ayurvedic medicine have been implied to the patient that showed new ray of life to the patient by relieving the complaints and presenting the negative report of HLA-B27.