No abstract

The aim of this study was to assess the evidence regarding the adoption and effectiveness of therapeutic procedures employed for rehabilitation of distal radius fractures. This systematic review used the following databases: PubMed, Lilacs, PEDro, Cochrane, Scielo and OTseeker, without time restrictions. The following keywords were searched for: distal radius fracture, rehabilitation, occupational therapy, physiotherapy including reports in English, Spanish, French, and Portuguese. Twenty-two studies were retrieved and analyzed by two independent investigators following the PEDro scale criteria. Other non-experimental studies were included for additional information regarding certain rehabilitation approaches. Of the 14 randomized controlled clinical trials, four compared early mobilization to

retreatment regimens, which allows continuous or paused therapeutic schemes. This study aims to perform cost-effectiveness and cost-utility analyses of biologic alternatives for moderate to severe psoriasis in Venezuela, from a public payer=s perspective. METHODS: A decision-tree model simulates psoriasis evolution after treatment with etanercept continuous (50mg twice a week for 12 weeks, followed by 25mg twice a week) or paused (12-week treatment cycle and 12-week interruption), adalimumab (80mg at first week, followed by 40mg in the second week, then 40mg every 2 weeks), infliximab (5 mg/kg at weeks 0, 2 and 6, then every 8 weeks) or ustekinumab (45mg in weeks 0 and 4, then 45mg every 12 weeks) and their associated costs in a 96-week time horizon. Therapy continuation or switch was evaluated at week 24. Effectiveness measures were PASI 75 success rate and quality adjusted life years (QALY) gained. Costs included biologicals, medical follow-up and adverse events management, from Venezuela official databases (values represented 2010 USD). Probabilistic sensitivity analyses were performed through Monte Carlo simulation. A 5% discount rate was applied for costs and benefits. RESULTS: Effectiveness resulted in [

These analyses include 60 participants that have completed the 12 month DIALBEST intervention that includes 17 home‐based peer counseling (PC) educational sessions in the topics of nutrition, diabetes and medication management. There were 930 PC contacts with patients with an average duration of 88 minutes per contact. The majority of sessions focused on nutrition (370) followed by diabetes complications (159). Participants evaluated the diabetes complications and food label sessions as very good/excellent (90%), the diabetes and medication management information as very good/excellent (88%), the portion size sessions as very good/excellent (85%), and the physical activity intervention as very good/excellent (83%). When asked about lifestyle changes, patients reported: eating out less (87%), eating less fast food (83%), planning their meals more (77%), being more physically active, routinely checking their feet (73%), eating lower fat foods and using food labels more (71%), as a result of their participation in DIALBEST. Funded by The Connecticut Center for Eliminating Health Disparities among Latinos (NIH‐NCMHD grant # P20MD001765).Grant Funding Source: Nutrion (ASN)