Wound healing entails a sequence of complex biological processes, which is a protective function of the body that focuses on a quick recovery. Reducing wound healing time is crucial in a wound as it lowers the chance of infection and decreases complications and costs. Papaya extract was obtained by a maceration method. It contains papain enzyme, flavonoid, saponin, and alkaloid, which act as an anti-inflammatory, astringent substance, vasodilator, antioxidant, analgesic, with antifungal, and antibacterial properties, and increase the collagen synthesis. This study aimed to assess the effect of Carica papaya extract application toward incised wound healing process in mice (Mus musculus) clinically and histologically. This experimental laboratory study was performed using 24 mice weighing between 30 and 40 grams and 12 and 14 weeks of age as experimental animals. Each group was incised along 5 mm at the labial gingiva under both of mandible anterior teeth with a depth reaching alveolar bone. Papaya extract was applied topically in the morning and evening for 14 days. The clinical result was obtained by assessing the length of wound closure measured every day for 14 days. Based on the statistic test result, it showed that the papaya extract has a significant effect (p ≤ 0.05) toward the healing process of an incised oral wound in mice. Histologically at day 14, 75% concentration papaya extract showed perfect epithelial layer and fibrillation.

Kepercayaan diri dalam interaksi sosial dan karakteristik psikologis individu dapat dipengaruhi oleh senyum yang estetik. Seseorang dapat dianggap ramah, populer, mudah bergaul, dan cerdas serta lebih menunjukkan perilaku yang positif bila memiliki senyum estetik. Seseorang yang memiliki senyum estetik akan lebih dapat diterima dalam masyarakat. Senyum yang estetik dapat dijadikan sebagai indikator evaluasi pasca perawatan. Penilaian terhadap senyum biasanya bersifat subjektif dan dipengaruhi oleh persepsi individu. Persepsi setiap individu dapat dipengaruhi oleh faktor usia, jenis kelamin dan pendidikan. Penelitian ini bertujuan untuk melihat persepsi terhadap senyum estetik. Penelitian dilakukan terhadap mahasiswi kedokteran gigi Universitas Syiah Kuala angkatan 2015-2016. Subjek dipilih sesuai kriteria inklusi, yang terdiri dari 58 orang yang dikelompokkan menjadi 6 kelompok. Subjek diminta mengisi kuesioner yang berisikan 7 pertanyaan. Masing-masing pertanyaan menampilkan 3 foto. Jawaban yang dipilih subjek dihitung menggunakan perhitungan Landis dan Koch. Hasil penelitian menunjukkan 86,2% subjek memiliki persepsi sangat baik dan baik, 13,8% subjek memiliki persepsi sedang sampai buruk. Kesimpulan penelitian ini adalah persepsi mahasiswi Kedokteran Gigi angkatan 2015-2016 Universitas Syiah Kuala terhadap senyum estetik adalah baik.

Streptococcus mutans is a Gram-positive facultative anaerobic bacteria which has become the main cause of dental caries. Black pepper (Piper nigrum L ) is one of herbal plants that compose antibacterial compounds including alkaloids, flavonoids, tannins, and essential oils. This study aims to determine the effect of black pepper (Piper nigrum L.) extract to inhibit of Streptococcus mutansgrowth. Black pepper extracts ware made by using maceration method. The effect of black pepper extract ( Piper nigrum L. ) in inhibition of Streptococcus mutansgrowth by using the disc diffusion method on Mueller Hinton Agar media. The concentration of black pepper ( Piper nigrum L.) extracts used in this study were 6.25%, 12.5%, 25%, 50%, 75%. The results of this study were analyzed by using the one-way ANOVA test showed that there was significant effect of black pepper extract on Streptococcus mutans growth with p-value (p <0.05), and then the data was tested by Least Significant Difference (LSD). Conclusion of this study showed that there was an effect of black pepper ( Piper nigrum L.) extract in inhibition of Streptococcus mutans growth with concentrations 75% is the optimum concentration which value 16.8 mm.

Aim: The aim of the study was to investigate the immunomodulatory activity of areca nut extract. The phytochemical content and phenolic composition of the extract were also determined. Materials and Methods: An extract of areca nut was prepared using 96% ethanol and subsequently screened for phytochemical content using a high-performance liquid chromatography (HPLC) method. The immunomodulatory activity of the extract was tested in 35 Sprague-Dawley rats, divided into four groups: One control group and three experimental groups in which the rats received 500, 1000, or 1500 mg/kg of oral areca nut extract biweekly (BW). The extract was orally administered 14 days before the intraperitoneal challenge with Staphylococcus aureus (1×108 CFU/mL). On the 14th day of the experiment, rats in all the four groups were sacrificed. Measurement of the levels of red blood cells, hematocrit (Hct), hemoglobin (Hb), white blood cells (WBCs), lymphocytes, monocytes, neutrophils, basophils, eosinophil, and macrophages were recorded. The activities of serum glutamate oxalate transaminase, serum glutamate pyruvate transaminase, urea, and creatinine were also determined. Results: Areca nut was found to contain an alkaloid, tannin, and flavonoid compounds. HPLC analysis revealed the presence of catechin as the major compound along with quercetin. Administration of areca nut extract in rats infected with S. aureus produced a significant increase in the concentration of WBC but did not affect Hct, Hb, and other cell types. Among the different doses tested, 1000 mg/kg BW was found to be most effective in cellular immunity models. No harmful effects on the liver and kidney functions were observed. Conclusion: The antioxidant activity of areca nut might be attributed to the presence of catechin and quercetin. Administration of areca nut extract increased the number of WBCs and improved the activity and capacity of macrophages significantly in rats infected with S. aureus.

Dental radiografi merupakan bagian dari radiologi kedokteran gigi yang bertujuan untuk melihat manifestasi oral di rongga mulut yang tidak dapat dilihat secara klinis. Unit radiologi yang melayani dental radiografi ini merupakan salah satu unit yang terdapat di Rumah Sakit Gigi dan Mulut (RSGM) Unsyiah. Kualitas pelayanan kesehatan terkait erat dengan kepuasan pasien baik secara medis maupun non medis. Tujuan penelitian adalah untuk mengetahui pengaruh kualitas pelayanan terhadap kepuasan pasien pada unit radiologi di RSGM Unsyiah. Jenis penelitian ini adalah penelitian analitik. Pengambilan subjek menggunakan metode purposive sampling dan sesuai dengan kriteria inklusi. Pengumpulan data dilakukan dengan pembagian kuisioner kepada subjek penelitian yang telah diberi informed consent. Hasil penelitian menunjukkan bahwa terdapat pengaruh kualitas pelayanan terhadap kepuasan pasien dalam bidang radiologi di RSGM Unsyiah. Subjek penelitian sebanyak 63 orang. Kualitas pelayanan didominasi oleh kategori baik sebanyak 32 orang (50,8%), dan kepuasan didominasi oleh kategori puas sebanyak 32 orang (50,8%). Berdasarkan hasil uji chi-square menunjukan nilai p= 0,000 < α 0,05. Dapat disimpulkan bahwa kualitas pelayanan memiliki pengaruh yang signifikan terhadap kepuasan pasien.