With the high demand for wireless data traffic, WiFi networks have experienced very rapid growth, because they provide high throughput and are easy to deploy. Recently, Channel State Information (CSI) measured by WiFi networks is widely used for different sensing purposes. To get a better understanding of existing WiFi sensing technologies and future WiFi sensing trends, this survey gives a comprehensive review of the signal processing techniques, algorithms, applications, and performance results of WiFi sensing with CSI. Different WiFi sensing algorithms and signal processing techniques have their own advantages and limitations and are suitable for different WiFi sensing applications. The survey groups CSI-based WiFi sensing applications into three categories, detection, recognition, and estimation, depending on whether the outputs are binary/multi-class classifications or numerical values. With the development and deployment of new WiFi technologies, there will be more WiFi sensing opportunities wherein the targets may go beyond from humans to environments, animals, and objects. The survey highlights three challenges for WiFi sensing: robustness and generalization, privacy and security, and coexistence of WiFi sensing and networking. Finally, the survey presents three future WiFi sensing trends, i.e., integrating cross-layer network information, multi-device cooperation, and fusion of different sensors, for enhancing existing WiFi sensing capabilities and enabling new WiFi sensing opportunities.
Recognizing the transportation modes of people's daily living is an important research issue in the pervasive computing. Prior research in this field mainly uses Global Positioning System (GPS), Global System for Mobile Communications (GSM) or their combination with accelerometer to recognize transportation modes, such as walking, driving, etc. In this paper, we will introduce transportation mode recognition on mobile phones only using embedded accelerometer. In order to deal with uncertainty of position and orientation of mobile phone, acceleration synthesization based method and acceleration decomposition based method are introduced. Performance comparison indicates that acceleration synthesization based method outperforms acceleration decomposition based method. We will discuss the factors affect the recognition accuracy of acceleration decomposition based method and present potential improvements.
Blockade of human ether-à-go-go related gene (hERG) channel by compounds may lead to drug-induced QT prolongation, arrhythmia, and Torsades de Pointes (TdP), and therefore reliable prediction of hERG liability in the early stages of drug design is quite important to reduce the risk of cardiotoxicity-related attritions in the later development stages. In this study, pharmacophore modeling and machine learning approaches were combined to construct classification models to distinguish hERG active from inactive compounds based on a diverse data set. First, an optimal ensemble of pharmacophore hypotheses that had good capability to differentiate hERG active from inactive compounds was identified by the recursive partitioning (RP) approach. Then, the naive Bayesian classification (NBC) and support vector machine (SVM) approaches were employed to construct classification models by integrating multiple important pharmacophore hypotheses. The integrated classification models showed improved predictive capability over any single pharmacophore hypothesis, suggesting that the broad binding polyspecificity of hERG can only be well characterized by multiple pharmacophores. The best SVM model achieved the prediction accuracies of 84.7% for the training set and 82.1% for the external test set. Notably, the accuracies for the hERG blockers and nonblockers in the test set reached 83.6% and 78.2%, respectively. Analysis of significant pharmacophores helps to understand the multimechanisms of action of hERG blockers. We believe that the combination of pharmacophore modeling and SVM is a powerful strategy to develop reliable theoretical models for the prediction of potential hERG liability.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.