Hydrogen bond has dual property, classical (electrostatic interaction based on Coulomb's law) and quantum (wave function based on Schrödinger equation). Since Planck's constant is one of the main criteria for decision which process is quantum, or how much is close to be quantum, we use electrical and magnetic forces of valence electrons, as point of departure, to develop method for opto-magnetic fingerprint of matter. During the study of different type of matter we observed phenomena from spectral convolution data of digital images which characterize matter from both covalent and non-covalent bonding. Since water is matter that is most abundant with hydrogen bonds, we present results of 18.2 MΩ water investigation on different temperature and under influence of constant and variable magnetic fields by opto-magnetic method. Bearing in mind that Linus Pauling, in his book Nature of the Chemical Bond (Cornel University Press, 1939), for the first time presented the systematic concept of the hydrogen bond to the molecular world and its machinery, this paper is written in honor to him and 70th anniversary of one of the most important scientific paradigm.

Background: Fullerene water complex establishes the optimal order and function of biomolecules in natural, biophysical way by transducing the signal through water hydrogen bonds to biomolecules.Objectives: This paper considers the effects of the patented hyper-harmonized-hydroxylated fullerene water complex (3HFWC) on biophysical properties of the skin collagen molecules.Method: Optomagnetic imaging spectroscopy (OMIS) has been used for the analysis of the biophysical skin properties (diamagnetic/paramagnetic) after applying three groups of different cosmetic products. Tested cosmetic products were prepared by replacing the active ingredients with 3HFWC or with water in four commercial products. The original commercial creams and their vehiculums with water added served as control groups. Data were statistically analyzed using paired t test in R software.Results: t Test gave statistically significant results for all of the products with 3HFWC, while within the control group, only body lotion and hand cream did show statistically significant results (P < 0.05). Significant improvements in abundance and quality of collagen in the dermis were achieved with body lotion with 3HFWC (p + /p − ranged from 0.82 to 0.97). While body lotion vehiculum made collagen-water interaction more stable (p + /p − ranged from 0.3 to 0.55), hand cream with 3HFWC made it more dynamic (p + /p − ranged from 0.63 to 0.49). Body lotion vehiculum improved the compactness of the dermis (p + /p − ranged from 0.2 to 1.03), as well as commercial hand cream (p + /p − ranged from 0.28 to 0.85). Conclusion:Compared to the control groups, cosmetic products with 3HFWC demonstrated positive effects on the biophysical properties of the skin. Increased paramagnetic properties are linked to more unpaired electrons, their faster movement, and, finally, better signal transduction. Thus, products with 3HFWC could enable faster regeneration of collagen and prompt skin reaction to the negative environmental influences.

Background Hyper Harmonized Hydroxyl Modified Fullerene Substance (3HFWC+) establishes hydrogen bonds with the surrounding water molecules and organizes them in clusters with the liquid crystalline state, similar to the properties of water surrounding the biomolecules. Aims To investigate the moisturizing properties of hyperharmonized fullerenol—3HFWC+ as an emulsion O/W ingredient on the skin. Patients/Methods We have analyzed the reflexion of the blue light from the skin, in vivo, with different levels of moisturization and compared the influence of three groups of cosmetic products (with various active ingredients, 3HFWC+ or water in same percentage in the “vehiculum”) on skin moisturization by measuring paramagnetic/diamagnetic properties by Optomagnetic Imaging Spectroscopy. Results Regenerating Cream and Body Lotion have shown statistically significant increase of diamagnetic features predominantly in all 3 types of creams, while the Hand Cream formulations have not shown statistically significant results after 4 weeks of treatment. Anti‐aging cream with 3HFWC+ demonstrated statistically significant increase of paramagnetic properties of the skin (p+/p‐ from 0.90 to 0.62) and showed beneficial effects on information transfer and water content in stratum corneum. Conclusion Although it does not act as a classical moisturizing agent on the skin, 3HFWC+ can increase moisturization as a result of hydrogen bonds established among 3HFWC+ and water or biomolecules, liquid crystalline state of water in 3HFWC+ resembling the properties of water surrounding the biomolecules, and finally, liquid crystalline state of water in the products.

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The main aim of this study was to examine the effects of medium-term supplementation with an eight-herbs extract on running performance, biomarkers of antioxidant status and telomere length, and self-reported outcome measures of safety events in healthy men. Ten healthy young men (age 23.1±3.2 years, weight 73.7±9.9kg, and height 179.4±8.0cm) volunteered to participate in this randomized controlled trial. The participants were allocated in a double-blind cross-over design to receive either an eight-herbs extract or placebo during a 6-week intervention period. Two-way mixed analysis of variance (treatment vs. time interaction) revealed no significant differences for exercise performance outcomes and telomere length between groups (P>0.05). Compared with placebo, P-DNA provoked a significant rise in serum total antioxidant capacity (316.0±183.4µmol/mL at baseline; 792.7±68.1µmol/mL at follow-up in the eight-herbs extract group vs. 298.1±90.7µmol/mL at follow-up in the placebo group; P<0.001), and less reduction in serum superoxide dismutase levels at follow-up (150.4±5.1IU/mL at baseline; 145.5±3.0IU/mL at follow-up in the eight-herbs extract group vs. 139.3±3.3IU/mL at follow-up in the placebo group; P=0.01). No participant reported any side effects of either intervention. The eight-herbs extract can thus be recommended as a well tolerated dietary supplement that can enhance antioxidant capacity in healthy men. This trial was registered at ClinicalTrials.gov (NCT04263246).