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The response of giant lymph node hyperplasia (Castleman's disease) to surgery is well known and surgery is the main technique in the management of these patients. We describe a young man who presented with clinical features suggestive of a lymphoma, but who was diagnosed to have Castleman's disease after histopathology. Complete response to radiation and a disease-free follow- up of 22 months prompts us to advocate radiation as an effective alternative mode of therapy in inoperable cases. Giant lymph node hyperplasia or Castleman's disease is a benign condition with enlargement of the lymph nodes, particularly common in the mediastinum. The patients are otherwise usually asymptomatic but may sometimes present with fever, anaemia, hyper-gammaglobulinaemia (Bartoli et al, 1980; Frrizera et al, 1983) and multi-centric lymph node enlargement (Gaba et al, 1978) mimicking a lymphoma.

In cervical cancer, the volume of disease as assessed on MRI may be a better prognostic indicator than FIGO staging and needs further evaluation.

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