Endoscopic retrograde pancreatogram and postmortem pancreatograms were compared in 6 dogs. The main duct, branches and acini of the pancreas were opacified adequately in that order with infusion of each 1 ml of contrast medium on 4 occasions in endoscopic retrograde pancreatography, and infusion of each 0.1 ml of the contrast medium on 4 occasions in postmortem pancreatography, respectively. The two pancreatograms were almost identical to the appearance of the main duct, branches and acini. The results suggest that a postmortem retrograde pancreatogram in order to investigate the correlation between the pancreatogram and the histological findings of the pancreas.
A 49-year-old man was admitted to our hospital with mild proteinuria. Prior to admission, he had been diagnosed as having Sjögren's syndrome in association with primary biliary cirrhosis. Examination of a renal biopsy under light microscopy revealed diffuse and global mesangial cell proliferation and a spike and/or bubbling formation of the glomerular basement membrane (GBM), resembling membranoproliferative glomerulonephritis. In contrast, immunofluorescent studies showed marked immunoglobulin and complement depositions in the mesangial areas; however, only faint granular IgG and IgA deposition was observed along the GBM. Interestingly, electron microscopy revealed that a microtubular structure, derived from podocytes, was present in the GBM. We present a case of glomerulopathy showing podocytic infolding in association with Sjögren's syndrome and primary biliary cirrhosis.
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