Objective: to analyze the structural state of the central area of the retina in diabetic macular edema in the background anti-VEGF therapy.Methods. The study included 38patients (40eyes) with diabetic macular edema. All patients received anti-VEGF-ranibizumab therapy at a dose of 0.05ml. The results were analyzed after three intravitreal injections with 1month interval. We assessed visual acuity, morphological and anatomical structure of the macular area, the sensitivity of the retina and macular pigment optical densityResults. Analyzing optical density of the macular pigment we revealed a significant increase of all parameters in 73% of patients after the therapy. The average value of the optical density before treatment was at 0.102±0.01du, on the background of anti-VEGF-therapy this figure went up to 0.213±0.01 (p<0.05). According to the optical coherence to-mography average retinal thickness before treatment made 404.62±15.23μm, after the treatment – 300.91±6.43μm (р<0,05). When comparing data of optical coherence tomography and macular pigment optical density we revealed more pronounced decrease in the macular pigment optical density in the area of the retinal edema and a significant increase in the basic parameters on the background of the therapy.Conclusion. Anti-VEGF-therapy significantly improves visual acuity, the recovery profile of macular edema and reduces the zone in patients with diabetic macular edema.
The review article presents the main results of the activity of JSC TC “Tatmelioratsiya” and “Tatmeliovodkhoz” administration on the land-reclamation work in the Republic of Tatarstan. These works included the repair, reconstruction of dams and ponds, the restoration and construction of new irrigation systems, commissioning and start-up of new fuel-efficient sprinklers. At January 1, 2011 a complete inventory of the technical condition of existing hydraulic structures was carried out by the JSC TC “Tatmelioratsiya”. There are 298 waterworks, that require repair and reconstruction in the Republic of Tatarstan. At the same time, it should be noted, because of the intensive use of constructed facilities at different time of natural disasters, the 52 dams was partially destroyed and require urgent measures to restore them. Among the emergency, the greatest danger in case of emergencies during the flood were 18 waterworks, where in case of emergency there is a real threat of flooding populated areas and economic facilities located in the flooded areas. The government of the Republic had provided funding for the anti-flood measures in 2011 in the amount of 40 million rubles, moreover, a republican target program for 2012- 2014 on the repair and reconstruction of hydraulic structures for the prolongation until 2017 was developed and adopted. The programs, passed by the Russian government and the Republic of Tatarstan, allow to strength food security and reduce import substitution of basic foods that will eventually contribute to the development of their own agricultural sector.
Russia’s accession to the WTO implies the emergence of fundamentally new economic conditions of functioning of the agrarian sector of the economy. At the same time a particular importance were obtained the problems of ensuring high competitiveness of domestic agricultural products and the preservation of the country’s food security. In the current challenging economic environment, despite a lot of objective and subjective reasons, the domestic food products must be price competitive, adequate for consumers. The entities of agribusiness is necessary to retain our market niche, the maximum filling capacity of the domestic market of food. The capacity of the domestic food market today is huge in almost all positions. The level of consumption of basic food for most types of lower medical nutritional standards.
The existing threats and risks in connection with Russia’s WTO accession necessitated the development of tools, aimed to protect troubled industries of agriculture and to ensure the development of a competitive agricultural sector of Russia. Therefore, an improvement of the system and mechanisms of state regulation of agriculture development of the Russian regions and the country as a whole becomes highly urgent.
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