Objective: Our aim was to examine the predictors of cardiovascular disorders in children affected by obstructive sleep apnea syndrome (OSAS) based on the results of polysomnography and continuous monitoring of blood glycose. Мethods: Before the examination, parents filled in questionnaires concerning their children sleep quality. The procedure was followed by the study of the sleep by means of polysomnography (Embla s 7000, USA).A system of continuous monitoring of blood glucose was applied (Guardianreal-time, Medtronicminimed, USA) by means of which a glycemic profile tissue fluid was studied. Results: A night sleep research of 120 children aged 3-16 y.o. is presented. There were 4 groups depending on the pathology: diseases of the nervous system (n =31), bronchial asthma (n =24) and overweight and obesity (n =34 (Вестник РАМН. 2015; 1: 32-40) АКТУАЛЬНЫЕ ВОПРОСЫ ПЕДИАТРИИ

No abstract

ВВЕДЕНИЕОдной из серьезных проблем здравоохранения XXI в., по оценке Всемирной организации здравоохра-нения, является ожирение -основной фактор сердеч-но-сосудистых заболеваний и сопутствующих осложне-ний. На сегодняшний день более 1,5 млрд людей старше 15 лет во всем мире имеют повышенный индекс массы тела (ИМТ), 1/3 из них страдает ожи рением [1,2].По прогнозу, проблема ожирения в России, как и во всем мире, будет только нарастать [3]. Особую тре-вогу вызывает распространенность патологии среди детского населения. По данным проведенных в раз-личных регионах Российской Федерации исследований, частота встречаемости избыточной массы тела среди подростков в возрасте 12-17 лет достигает 12% [4][5][6]. Вызы вают беспокойство и темпы роста распростра-ненности ожирения: так, повышенный ИМТ в возраст-ной категории 12-20 лет имеют 6,9-11,8% мужчин и 13,7-16,6% женщин. Дальнейшие длительные наблюде-ния демонстрируют только увеличение распространен-ности заболевания -до 52,2% у мужчин и до 34,8% у женщин к 35 годам жизни [7]. Безусловно, патологиче-ские процессы ожирения среди населения, принявшие масштабы эпидемии, связаны в том числе и с объектив-

BackgroundIt was marked that children with increased BMI have high height due to insulin resistance or elevating insulin/IGF1. The Insulin resistant can be reason of cardio-vascular diseases.Aimto find the early detection of risk factors for cardiovascular diseases in children with height≥85 percentile age-sex normMethods854 children aged 3–17 y.o. were examined (included 87 with height≥85 percentile): by arterial stiffness device (TensioMed,Hungary) – 211; by 24 hour monitoring of ECG and blood pressure(Astrocard, Russia) – 92; by Polysomnography (Embla-S7000,USA)- 45; by system of continuous glucose monitoring (Guardian, USA) – 14 children.ResultsChildren with increased BMI and with height≥85 percentile in comparison with middle height had a significantly lower augmentation index, in 5 times more often – decreased diastolic blood pressure at night, lower level of high density lipoproteids; if they had obesity- the normal 24 hour dynamics of blood pressure was disappeared, if they had overweight- there was more longer QT interval at night, if they had sleep obstructive apnea-hypopnea syndrom there were some periods of glycemia less then 3.3 mmol/L at night.ConclusionsChildren with height≥85 percentile of age- and gender-based norms with increased BMI and, especially, with nasal obstruction have an additional risk of cardio-vascular diseases.Disclosure of InterestNone Declared