III-V/Ge CMOS on Si platform, realized by heterogeneous integration, is expected to provide a variety of applications from high speed logic CMOS to versatile SoC chips, where various functional devices can be co-integrated. Among them, high speed/low power logic CMOS using III-V/Ge channels are promising device solution for further progress in scaled CMOS. While many critical issues have been well recognized for them, we present possible solutions to break through these difficulties in this paper. Main critical issues of Ge/III-V MOSFETs on Si platform are (1) formation of MIS gate stacks with superior interfacial properties and (2) formation of Ge/III-V channel layers on Si substrates. Ge MOS interfaces with thermally-oxidized GeO 2 are promising for the superior interface properties as well as the high inversion-layer mobility. SGOI/GOI structures based on Ge condensation are promising for future ultrathin SGOI/GOI MOSFETs. A wafer bonding technique can be potential solutions of III-V MOSFETs on Si platform. Using this technique, the operation of ultrathin body/ultrathin BOX InGaAs-OI MOSFETs are demonstrated. Also, surface nitridation and surface orientation engineering are shown to be effective in III-V MOS interface control. Finally, novel metal S/D InGaAs MOSFETs utilizing NiInGaAs alloys are proposed and demonstrated.